Oleoyl proline | 107432-37-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Oleoyl proline
• 英文别名: (2S)-1-[(Z)-octadec-9-enoyl]pyrrolidine-2-carboxylic acid
• CAS: 107432-37-1
• 化学式: C₂₃H₄₁NO₃
• 分子量: 379.6
• InChiKey: WQCMZYCKACKLDL-YUQDSPFASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  27
• 可旋转键数：
  16
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  57.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• 1-(Alkenoyl) Azacycloalkyl carboxylic acids and derivatives
  申请人：G.D. Searle & Co.

  公开号：EP0208279A1

  公开（公告）日：1987-01-14

  This invention relates to 1-(alkenoyl)azacycloalkyl carboxylic acids and derivatives that prevent or reduce the degradation of elastin and other proteins and that thereby prevent or retard the disease states caused by said degradation.

  本发明涉及 1-(烯酰基)氮杂环烷基羧酸及其衍生物，可防止或减少弹性蛋白和其他蛋白质的降解，从而预防或延缓由上述降解引起的疾病状态。
• DETECTION MARKER FOR COLONIC LESIONS
  申请人：THE GENERAL HOSPITAL CORPORATION

  公开号：EP0318502A1

  公开（公告）日：1989-06-07
• US4649147A
  申请人：——

  公开号：US4649147A

  公开（公告）日：1987-03-10
• [EN] DETECTION MARKER FOR COLONIC LESIONS
  申请人：THE GENERAL HOSPITAL CORPORATION

  公开号：WO1988001301A1

  公开（公告）日：1988-02-25

  (EN) A method for the detection of neoplastic disease of the colon in an RNA containing colonic sample, which comprises contacting the RNA of the sample with a detectably labeled H-LTR or H-$i(env) nucleotide probe; and detecting the amount of hybridization between the probe and the RNA, relative to the amount in a known, non-cancerous, colonic sample.(FR) Le procédé de détection de maladies néoplastiques du colon consiste à prélever un échantillon du colon contenant un ARN et à mettre en contact l'ARN de l'échantillon avec une sonde de nucléotides H-LTR ou H-$i(env) marquée de manière détectable, puis à détecter la quantité d'hybridation entre la sonde et l'ARN et à comparer cette quantité à la quantité connue d'un échantillon de colon non cancéreux.
• [EN] TRANSPARENT SHAMPOO BAR AND METHOD FOR PREPARING THE SAME<br/>[FR] SHAMPOING SOLIDE TRANSPARENT ET SA MÉTHODE DE PRÉPARATION
  申请人：HENKEL AG & CO KGAA

  公开号：WO2021212404A1

  公开（公告）日：2021-10-28

  It relates to a method for producing a transparent shampoo bar, comprising: i) preparing a solution i) comprising at least one N-acyl amino acid and water, the solution i) having a temperature of 70 ℃ to 100 ℃, preferably 75 ℃ to 90 ℃, more preferably 80 ℃ to 88 ℃, ii) preparing a solution ii) comprising at least one alkali and water, the solution ii) having a temperature of 70 ℃ to 100 ℃, preferably 75 ℃ to 90 ℃, more preferably 80 ℃ to 88 ℃, iii) adding the solution ii) to the solution i) with stirring at a temperature of 70 ℃ to 100 ℃, preferably 75 ℃ to 90 ℃, more preferably 80 ℃ to 88 ℃, so as to obtain a homogeneous transparent solution iii); and iv) cooling the solution iii) to room temperature, wherein a) at least one alcohol is comprised in the solution i) and/or the solution ii) and/or the solution iii), b) the water is comprised in a total amount of no more than 40 wt%, preferably no more than 30 wt%, based on the total weight of the transparent shampoo bar, and c) optionally, a second surfactant and/or a hair conditioning compound is/are comprised in the solution i) and/or the solution ii) and/or the solution iii). It also relates to the transparent shampoo bar produced by the method thereof.