N-(4-methoxyphenyl)-N-[4-(3-pyridylmethylaminocarbonylmethoxy)phenyl]amine | 632384-72-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: N-(4-methoxyphenyl)-N-[4-(3-pyridylmethylaminocarbonylmethoxy)phenyl]amine
• 英文别名: 2-[4-(4-methoxyanilino)phenoxy]-N-(pyridin-3-ylmethyl)acetamide
• CAS: 632384-72-6
• 化学式: C₂₁H₂₁N₃O₃
• 分子量: 363.416
• InChiKey: ULBCRLYFKRUVBA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  27
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  72.5
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• [EN] NITROSODIPHENYLAMINE DERIVATIVES, COMPOSITIONS COMPRISING THEM, AND THE USE THEREOF AS ANTIOXIDANTS AND SPONTANEOUS NITRIC OXIDE DONORS<br/>[FR] DERIVES NITROSODIPHENYLAMINIQUES, COMPOSITIONS LES COMPRENANT, ET LEUR UTILISATION COMME ANTIOXYDANTS ET COMME DONNEURS SPONTANES DE MONOXYDE D'AZOTE
  申请人：MERCK PATENT GMBH

  公开号：WO2003103567A2

  公开（公告）日：2003-12-18

  The invention relates to compounds of the general formula (I) in which R i, A, n, B and Z are as defined in Claim 1. These compounds can be used for the preparation of antioxidant medicinal products that function as free-radical scavengers or are useful in the treatment of pathologies characterised by an oxidative stress condition and a lack of availability of endothelial nitrogen monoxide. The invention also relates to the pharmaceutical compositions comprising them.