(alphaR)-N,alpha-Dipropylbenzeneethanamine | 784118-64-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (alphaR)-N,alpha-Dipropylbenzeneethanamine
• 英文别名: (2R)-1-phenyl-N-propylpentan-2-amine
• CAS: 784118-64-5
• 化学式: C₁₄H₂₃N
• 分子量: 205.34
• InChiKey: PBENSVGEGPJNFJ-CQSZACIVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Compounds for use in the prevention or treatment of cancer
  申请人：SEMMELWEIS UNIVERSITY

  公开号：US10258598B2

  公开（公告）日：2019-04-16

  The invention relates to the field of prevention and treatment of cancer, in particular suppression of tumor manifestation. The invention also relates to compounds for use in this field. A novel tumor manifestation suppression (TMS) regulation in a mammalian brain is recognized. The invention relates to compounds, pharmaceutical preparations, in particular medicaments for use in the prevention and treatment of cancer, in particular suppression of tumor manifestation based on said TMS regulation as well as methods for the same.

  本发明涉及癌症的预防和治疗领域，特别是抑制肿瘤的表现。本发明还涉及用于该领域的化合物。本发明确认了一种新型的哺乳动物大脑肿瘤表现抑制（TMS）调节方法。本发明涉及化合物、药物制剂，特别是用于预防和治疗癌症的药物，尤其是基于所述TMS调节的肿瘤表现抑制以及相关方法。
• Treatment of dermatological conditions via neuromodulation
  申请人：Palo Alto Investors

  公开号：US11383084B2

  公开（公告）日：2022-07-12

  Methods for treating a subject for a dermatological condition are provided. Aspects of the invention include administering an effective amount of a neuromodulatory agent to a subject to treat the subject for the dermatological condition. Also provided are compositions, kits and systems for practicing the subject methods.

  本发明提供了治疗受试者皮肤病的方法。本发明的各个方面包括向受试者施用有效量的神经调节剂，以治疗受试者的皮肤病。本发明还提供了用于实施上述方法的组合物、试剂盒和系统。
• ARYLALKYLAMINE COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF CANCER
  申请人：Semmelweis University

  公开号：EP3226851B1

  公开（公告）日：2020-03-18
• COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF CANCER
  申请人：SEMMELWEIS UNIVERSITY

  公开号：US20170340582A1

  公开（公告）日：2017-11-30

  The invention relates to the field of prevention and treatment of cancer, in particular suppression of tumor manifestation. The invention also relates to compounds for use in this field. A novel tumour manifestation suppression (TMS) regulation in a mammalian brain is recognized. The invention relates to compounds, pharmaceutical preparations, in particular medicaments for use in the prevention and treatment of cancer, in particular suppression of tumor manifestation based on said TMS regulation as well as methods for the same.
• Treatment of Dermatological Conditions via Neuromodulation
  申请人：Palo Alto Investors

  公开号：US20180311499A1

  公开（公告）日：2018-11-01

  Methods for treating a subject for a dermatological condition are provided. Aspects of the invention include administering an effective amount of a neuromodulatory agent to a subject to treat the subject for the dermatological condition. Also provided are compositions, kits and systems for practicing the subject methods.