(E)-3-[(2R,3R)-3-((1S,2R,3R)-4-Benzyloxy-1,3-dimethyl-2-triethylsilanyloxy-butyl)-oxiranyl]-acrylic acid ethyl ester | 177929-74-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-3-[(2R,3R)-3-((1S,2R,3R)-4-Benzyloxy-1,3-dimethyl-2-triethylsilanyloxy-butyl)-oxiranyl]-acrylic acid ethyl ester
• CAS: 177929-74-7
• 化学式: C₂₆H₄₂O₅Si
• 分子量: 462.702
• InChiKey: WYCOSBUSMXSSPN-AIXVFJJVSA-N

反应信息

• 作为反应物：
  描述：

  (E)-3-[(2R,3R)-3-((1S,2R,3R)-4-Benzyloxy-1,3-dimethyl-2-triethylsilanyloxy-butyl)-oxiranyl]-acrylic acid ethyl ester 在 四丁基氟化铵 作用下， 以 四氢呋喃 为溶剂， 生成 (E)-3-[(2R,3R)-3-((1R,2R,3R)-4-Benzyloxy-2-hydroxy-1,3-dimethyl-butyl)-oxiranyl]-acrylic acid ethyl ester
  参考文献：
  名称：

  Tandem synthesis of polypropionate chains–highly stereoselective synthesis of the ansa chain of streptovaricin U and protostreptovaricins based on stereospecific methylation of γ,δ-epoxy acrylates by trimethylaluminium

  摘要：

  The highly stereoselective synthesis of the ansa chain segment 23 of streptovaricin U and protostreptovaricins (I and II) is achieved by stereospecific methylation of gamma,delta-epoxy acrylates with trimethylaluminium.

  DOI：

  10.1039/cc9960001027
• 作为产物：
  描述：

  磷酰基乙酸三乙酯 、 3-((1S,2R,3R)-4-Benzyloxy-1,3-dimethyl-2-triethylsilanyloxy-butyl)-oxirane-2-carbaldehyde 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 生成 (E)-3-[(2S,3S)-3-((1S,2R,3R)-4-Benzyloxy-1,3-dimethyl-2-triethylsilanyloxy-butyl)-oxiranyl]-acrylic acid ethyl ester 、 (E)-3-[(2R,3R)-3-((1S,2R,3R)-4-Benzyloxy-1,3-dimethyl-2-triethylsilanyloxy-butyl)-oxiranyl]-acrylic acid ethyl ester
  参考文献：
  名称：

  Tandem synthesis of polypropionate chains–highly stereoselective synthesis of the ansa chain of streptovaricin U and protostreptovaricins based on stereospecific methylation of γ,δ-epoxy acrylates by trimethylaluminium

  摘要：

  The highly stereoselective synthesis of the ansa chain segment 23 of streptovaricin U and protostreptovaricins (I and II) is achieved by stereospecific methylation of gamma,delta-epoxy acrylates with trimethylaluminium.

  DOI：

  10.1039/cc9960001027