N²-DL-alanyl-L-asparagine | 20051-99-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N²-DL-alanyl-L-asparagine
• 英文别名: N²-DL-Alanyl-L-asparagin；(2S)-4-amino-2-(2-aminopropanoylamino)-4-oxobutanoic acid
• CAS: 20051-99-4
• 化学式: C₇H₁₃N₃O₄
• 分子量: 203.198
• InChiKey: CCUAQNUWXLYFRA-BKLSDQPFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.8
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  136
• 氢给体数：
  4
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 氨 、 水 作用下， 生成 N²-DL-alanyl-L-asparagine
  参考文献：
  名称：

  Grassmann; Mayr, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1933, vol. 214, p. 210

  摘要：

  DOI：

文献信息

• Process for producing dipeptide,l-amino acid amide hydrolase to be used therein and process for producing l-amino acid amide hydrolase
  申请人：Nozaki Hiroyuki

  公开号：US20050054067A1

  公开（公告）日：2005-03-10

  A process for industrially advantageously producing a dipeptide via a convenient pathway starting with less expensive and easily available materials is provided. A dipeptide is produced from an L-amino acid amide and an L-amino acid by using a culture of a microbe capable of synthesizing the dipeptide from the L-amino acid amide and the L-amino acid, microbial cells separated from the culture or a treated microbial cell product from the microbe. An L-amino acid amide hydrolase is obtained from a microbe belonging to the genus erwinia, genus Rhodococcus, genus Chryseobacterium, genus Micrococcus, genus Cryptococcus, genus Trichosporion, genus Rhodosporidium, genus Sporobolomyces, genus Tremela, genus Torulaspora, genus Sterigmatomyces or genus Rhodotorula. The hydrolase catalyzes a reaction that produces a dipeptide from an L-amino acid amide and an L-amino acid.

  提供一种工业上优势的方法，通过一个便捷的途径，使用成本较低且易得的材料开始，生产二肽。通过使用能够从L-氨基酸酰胺和L-氨基酸合成二肽的微生物培养物，从培养物中分离的微生物细胞或经过处理的微生物细胞产物来制备二肽。从属于Erwinia属，Rhodococcus属，Chryseobacterium属，Micrococcus属，Cryptococcus属，Trichosporion属，Rhodosporidium属，Sporobolomyces属，Tremela属，Torulaspora属，Sterigmatomyces属或Rhodotorula属的微生物中获得L-氨基酸酰胺水解酶。该水解酶催化从L-氨基酸酰胺和L-氨基酸产生二肽的反应。
• Dipeptide production method, L-amino acid amide hydrolase used therein, and production method of L-amino acid amide hydrolase
  申请人：Nozaki Hiroyuki

  公开号：US20070042459A1

  公开（公告）日：2007-02-22

  A process for industrially advantageously producing a dipeptide via a convenient pathway starting with less expensive and easily available materials is provided. A dipeptide is produced from an L-amino acid amide and an L-amino acid by using a culture of a microbe capable of synthesizing the dipeptide from the L-amino acid amide and the L-amino acid, microbial cells separated from the culture or a treated microbial cell product from the microbe. An L-amino acid amide hydrolase is obtained from a microbe belonging to the genus erwinia, genus Rhodococcus, genus Chryseobacterium, genus Micrococcus, genus Cryptococcus, genus Trichosporion, genus Rhodosporidium, genus Sporobolomyces, genus Tremela, genus Torulaspora, genus Sterigmatomyces or genus Rhodotorula. The hydrolase catalyzes a reaction that produces a dipeptide from an L-amino acid amide and an L-amino acid.

  提供了一种通过方便的途径从成本较低且易获得的材料开始，工业上有利地生产二肽的过程。使用能够从L-氨基酸酰胺和L-氨基酸合成二肽的微生物培养物、从培养物中分离的微生物细胞或经过处理的微生物细胞产物来从L-氨基酸酰胺和L-氨基酸中生产二肽。从属于Erwinia属、Rhodococcus属、Chryseobacterium属、Micrococcus属、Cryptococcus属、Trichosporion属、Rhodosporidium属、Sporobolomyces属、Tremela属、Torulaspora属、Sterigmatomyces属或Rhodotorula属的微生物中获得L-氨基酸酰胺水解酶。该水解酶催化从L-氨基酸酰胺和L-氨基酸生成二肽的反应。
• PROCESS FOR PRODUCING DIPEPTIDE, L−AMINO ACID AMIDE HYDROLASE TO BE USED THEREIN AND PROCESS FOR PRODUCING L−AMINO ACID AMIDE HYDROLASE
  申请人：Ajinomoto Co., Inc.

  公开号：EP1411060A1

  公开（公告）日：2004-04-21

  A process for industrially advantageously producing a dipeptide via a convenient pathway starting with less expensive and easily available materials is provided. Namely, a dipeptide is produced from an L-amino acid amide and an L-amino acid by using a culture of a microbe capable of synthesizing the dipeptide from the L-amino acid amide and the L-amino acid, microbial cells separated from the culture or a treated microbial cell product from the microbe.

  本发明提供了一种工业化生产二肽的工艺，该工艺通过便捷的途径，以较低成本和易于获得的材料为起点，生产二肽。即，通过使用能够从 L-氨基酸酰胺和 L-氨基酸合成二肽的微生物培养物、从培养物中分离出的微生物细胞或从微生物中处理过的微生物细胞产物，用 L-氨基酸酰胺和 L-氨基酸生产二肽。
• A FEED COMPOSITION FOR CULTURING FISHES AND SHELLFISHES
  申请人：KYOWA HAKKO KOGYO CO., LTD.

  公开号：EP0357784A1

  公开（公告）日：1990-03-14
• US7037673B2
  申请人：——

  公开号：US7037673B2

  公开（公告）日：2006-05-02