2,4-Bis[4-[4-[4,6-bis(4-bromo-3-methylphenyl)-1,3,5-triazin-2-yl]-2-methylphenyl]-3-methylphenyl]-6-(4-iodo-3-methylphenyl)-1,3,5-triazine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,4-Bis[4-[4-[4,6-bis(4-bromo-3-methylphenyl)-1,3,5-triazin-2-yl]-2-methylphenyl]-3-methylphenyl]-6-(4-iodo-3-methylphenyl)-1,3,5-triazine
• 英文别名: 2,4-bis[4-[4-[4,6-bis(4-bromo-3-methylphenyl)-1,3,5-triazin-2-yl]-2-methylphenyl]-3-methylphenyl]-6-(4-iodo-3-methylphenyl)-1,3,5-triazine
• 化学式: C₁₀H₈NO₂PolS
• 分子量: 1491.8
• InChiKey: PKWXBWBFHSQQQE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  21
• 重原子数：
  86
• 可旋转键数：
  11
• 环数：
  12.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  116
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  苄基丙二酸二乙酯 、 2,4-Bis[4-[4-[4,6-bis(4-bromo-3-methylphenyl)-1,3,5-triazin-2-yl]-2-methylphenyl]-3-methylphenyl]-6-(4-iodo-3-methylphenyl)-1,3,5-triazine 在 potassium carbonate 作用下， 以 乙腈 为溶剂， 反应 0.5h， 生成 Diethyl 2-(benzenesulfinyl)-2-benzylpropanedioate
  参考文献：
  名称：

  Sulfenylation chemistry using polymer-supported sulfides

  摘要：

  Clean sulfenylations are observed upon reaction of activated methylenes with phenyl succinimidyl sulfide. When working with diethyl benzylmalonate, the sulfenylated product can be selectively oxidized and thermally fragmented affording phenylsulfenic acid, initially, and diethyl benzylidenemalonate. The developed method was applied using a polymer-supported thioanisole derivative (JandaJel). Formation of the enedicarboxylate documents proof of principle of polymer-supported sulfides as sulfenylating agents onto activated methylenes. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.02.009
• 作为产物：
  描述：

  2-[4-(4,4',5,5'-tetramethyl-1,3,2-dioxaborolyl)]-4,6-di(4-bromo-3-methylphenylene)-1,3,5-triazine 、 2,4,6-tris(4-iodo-3-methylphenylene)-1,3,5-triazine 在 四(三苯基膦)钯 、 sodium carbonate 作用下， 以 邻二甲苯 、 水 为溶剂， 反应 72.0h， 以79%的产率得到2,4-Bis[4-[4-[4,6-bis(4-bromo-3-methylphenyl)-1,3,5-triazin-2-yl]-2-methylphenyl]-3-methylphenyl]-6-(4-iodo-3-methylphenyl)-1,3,5-triazine
  参考文献：
  名称：

  Synthesis of a halo-methylphenylene periphery-functionalized triazine-based dendritic molecule with a 3,3′-dimethyl-biphenyl linker using tris(halo-methylphenylene)triazines as building blocks

  摘要：

  A tris(bromo-methylphenylene)triazine and its corresponding phosphine oxide derivative have been synthesized; the latter compound was found to be a potent ligand for the hydroformylation reaction. Suzuki coupling of the mono-pinacolboronate derivative of the former compound with a tris(iodo-methylphenylene)triazine was possible at two of the three iodine atoms, yielding a bromo- and iodo-methylphenylene periphery-functionalized triazine-based dendritic molecule with a 3,3 '-dimethyl-bipheny) linker. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.02.011

文献信息

• Sulfenylation chemistry using polymer-supported sulfides
  作者：David C. Forbes、Sampada V. Bettigeri、Nahla N. Al-Azzeh、Brian P. Finnigan、Joseph A. Kundukulam

  DOI：10.1016/j.tetlet.2009.02.009

  日期：2009.4

  Clean sulfenylations are observed upon reaction of activated methylenes with phenyl succinimidyl sulfide. When working with diethyl benzylmalonate, the sulfenylated product can be selectively oxidized and thermally fragmented affording phenylsulfenic acid, initially, and diethyl benzylidenemalonate. The developed method was applied using a polymer-supported thioanisole derivative (JandaJel). Formation of the enedicarboxylate documents proof of principle of polymer-supported sulfides as sulfenylating agents onto activated methylenes. (C) 2009 Elsevier Ltd. All rights reserved.
• Synthesis of a halo-methylphenylene periphery-functionalized triazine-based dendritic molecule with a 3,3′-dimethyl-biphenyl linker using tris(halo-methylphenylene)triazines as building blocks
  作者：Ioannis D. Kostas、Fotini J. Andreadaki、Elaine A. Medlycott、Garry S. Hanan、Eric Monflier

  DOI：10.1016/j.tetlet.2009.02.011

  日期：2009.4

  A tris(bromo-methylphenylene)triazine and its corresponding phosphine oxide derivative have been synthesized; the latter compound was found to be a potent ligand for the hydroformylation reaction. Suzuki coupling of the mono-pinacolboronate derivative of the former compound with a tris(iodo-methylphenylene)triazine was possible at two of the three iodine atoms, yielding a bromo- and iodo-methylphenylene periphery-functionalized triazine-based dendritic molecule with a 3,3 '-dimethyl-bipheny) linker. (C) 2009 Elsevier Ltd. All rights reserved.