carbamic acid heptadecanyl ester | 60653-89-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: carbamic acid heptadecanyl ester
• 英文别名: carbamic acid heptadecyl ester；heptadecyl carbamate
• CAS: 60653-89-6
• 化学式: C₁₈H₃₇NO₂
• 分子量: 299.497
• InChiKey: XSBIDHSRRHZHPZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.7
• 重原子数：
  21
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  52.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  、 1-十七烷醇 、 尿素 在 镍 作用下， 以280 parts of heptadecyl carbamate are obtained的产率得到carbamic acid heptadecanyl ester
  参考文献：
  名称：

  Manufacture of carbamates

  摘要：

  Carbamates是通过在含有镍的离子交换剂存在下，将醇与尿素反应制成的。该产品是制造纺织品整理剂、染料和植物保护剂的起始材料。

  公开号：

  US04156784A1

文献信息

• Method for Producing Carbonyl Compund
  申请人：Shinohata Masaaki

  公开号：US20130178645A1

  公开（公告）日：2013-07-11

  A method for producing a carbonyl compound of the present invention comprises a step (X) of reacting a specific compound having a urea bond with a carbonic acid derivative having a carbonyl group (—C(═O)—) under heating at a temperature equal to or higher than the thermal dissociation temperature of the urea bond to obtain the carbonyl compound.

  本发明的生产羰基化合物的方法包括以下步骤（X）：将具有脲键的特定化合物与具有羰基（—C(═O)—）的碳酸衍生物在温度高于或等于脲键热解温度的条件下加热反应，以获得所述羰基化合物。
• METHOD FOR PRODUCING CARBAMATE AND METHOD FOR PRODUCING ISOCYANATE
  申请人：ASAHI KASEI KABUSHIKI KAISHA

  公开号：US20210179548A1

  公开（公告）日：2021-06-17

  The present invention provides a method for producing a carbamate that includes a step (1) and a step (2) described below: (1) a step of producing a compound (A) having a urea linkage, using an organic primary amine having at least one primary amino group per molecule and at least one compound selected from among carbon dioxide and carbonic acid derivatives, at a temperature lower than the thermal dissociation temperature of the urea linkage; and (2) a step of reacting the compound (A) with a carbonate ester to produce a carbamate.

  本发明提供了一种生产碳酸酯的方法，包括以下步骤：(1)通过使用每个分子至少含有一个一次氨基团的有机初级胺和碳酸气体或碳酸衍生物中选择的至少一种化合物，在低于尿素键热解温度的温度下，生产具有尿素键的化合物(A)；以及(2)将化合物(A)与碳酸酯反应以生产碳酸酯。
• N-Substituted Carbamic Acid Ester Production Method, Isocyanate Production Method Using Such N-Substituted Carbamic Acid Ester, And Composition For Transfer And Storage Of N-Substituted Carbamic Acid Ester Comprising N-Substituted Carbamic Acid Ester and Aromatic Hydroxy Compound
  申请人：Shinohata Masaaki

  公开号：US20110133121A1

  公开（公告）日：2011-06-09

  The present invention is a method for producing an N-substituted carbamic acid ester derived from an organic amine from an organic amine, a carbonic acid derivative and a hydroxy composition containing one or more types of hydroxy compounds, wherein the organic amine, the carbonic acid derivative and the hydroxy composition are reacted using a urethane production reaction vessel provided with a condenser, a gas containing the hydroxy composition, the compound having the carbonyl group derived from the carbonic acid derivative, and an ammonia formed as a by-product in the reaction, is introduced into the condenser provided in the urethane production reaction vessel, and the hydroxy composition and the compound having the carbonyl group derived from the carbonic acid derivative are condensed, and wherein a stoichiometric ratio of a hydroxy compound contained in the condensed hydroxy composition to the condensed compound having the carbonyl group derived from the carbonic acid derivative is 1 or more, and a ratio of number of carbonyl groups (—C(═O)—) contained in the compound having the carbonyl group derived from the carbonic acid derivative and number of ammonia molecules contained in the ammonia recovered as a gas from the condenser is 1 or less.

  本发明涉及一种从有机胺、碳酸衍生物和含有一种或多种羟基化合物中制得的N-取代氨基甲酸酯的制备方法，其中使用一种含有冷凝器的脲类生产反应容器反应有机胺、碳酸衍生物和羟基化合物，将含有羟基化合物的气体、来自碳酸衍生物衍生的含有羰基基团的化合物、以及在反应中形成的氨气体引入到脲类生产反应容器中的冷凝器中，使羟基化合物和含有羰基基团的化合物冷凝，其中在冷凝的羟基化合物中所含有的羟基化合物与冷凝的含有羰基基团的化合物中所含有的羰基基团的化合物的比例为1或更多，而且在从冷凝器中回收的氨气体中所含有的羰基基团（—C(═O)—）数与氨分子数的比例为1或更少。
• N-Substituted Carbamic Acid Ester Production Method, Isocyanate Production Method Using Such N-Substituted Carbamic Acid Ester, and Composition for Transfer and Storage of N-Substituted Carbamic Acid Ester Comprising N-Substituted Carbamic Acid Ester and Aromatic Hydroxy Compound
  申请人：Asahi Kasei Chemicals Corporation

  公开号：US20140194650A1

  公开（公告）日：2014-07-10

  The present invention is a method for producing an N-substituted carbamic acid ester derived from an organic amine from an organic amine, a carbonic acid derivative and a hydroxy composition containing one or more types of hydroxy compounds, wherein the organic amine, the carbonic acid derivative and the hydroxy composition are reacted using a urethane production reaction vessel provided with a condenser, a gas containing the hydroxy composition, the compound having the carbonyl group derived from the carbonic acid derivative, and an ammonia formed as a by-product in the reaction, is introduced into the condenser provided in the urethane production reaction vessel, and the hydroxy composition and the compound having the carbonyl group derived from the carbonic acid derivative are condensed, and wherein a stoichiometric ratio of a hydroxy compound contained in the condensed hydroxy composition to the condensed compound having the carbonyl group derived from the carbonic acid derivative is 1 or more, and a ratio of number of carbonyl groups (—C(═O)—) contained in the compound having the carbonyl group derived from the carbonic acid derivative and number of ammonia molecules contained in the ammonia recovered as a gas from the condenser is 1 or less.

  本发明是一种从有机胺、碳酸酯衍生物和含有一种或多种羟基化合物中制备N-取代的氨基甲酸酯的方法，其中利用一种尿素生产反应容器反应有机胺、碳酸酯衍生物和羟基化合物，该反应容器配有冷凝器，将含有羟基化合物的气体、由碳酸酯衍生物产生的含有羰基基团的化合物以及在反应中生成的氨引入到尿素生产反应容器中的冷凝器中，将羟基化合物和含有羰基基团的碳酸酯衍生物冷凝，其中在冷凝的羟基化合物中所含的羟基化合物的化学计量比与所冷凝的含有羰基基团的化合物的化学计量比为1或更多，而且所含有羰基基团的化合物中所含的羰基基团（-C(═O)-）的数量与从冷凝器中回收的氨分子数量的比率为1或更小。
• Aminoglycoside derivatives, processes for their preparation and pharmaceutical compositions containing them
  申请人：FUJISAWA PHARMACEUTICAL CO., LTD.

  公开号：EP0107850A1

  公开（公告）日：1984-05-09

  Aminoglycoside derivatives of the formula: wherein at least one of R', R2, R3 and R4 is higher alkanoylamino, higher alkenoylamino, higher alkoxycarbonylamino, higher alkylaminocarbonylamino, higher alkoxy(lower)alkanoylamino or higher alkylthiocarbonyrm- no, each of which may have suitable substituent(s), and the others are amino or acylamino, R5 is hydroxy, amino or acylamino, R6 and R7 are each hydroxy or hydrogen, and R10 is hydroxy or phosphonoxy, and pharmaceutically acceptable salts thereof, processes for their preparations and pharmaceutical compositions containing them. The invention further relates to intermediates for preparing such compounds and processes for their preparation.

  式中的氨基糖苷衍生物： 其中 R'、R2、R3 和 R4 中至少有一个是高级烷酰基氨基、高级烯酰基氨基、高级烷氧基羰基氨基、高级烷基氨基羰基氨基、高级烷氧基（低级）烷酰基氨基或高级烷基硫代羰基氨基，每一个都可以有合适的取代基，其他的是氨基或酰基氨基、 R5是羟基、氨基或酰氨基，R6和R7各自是羟基或氢，R10是羟基或磷酰氧基，以及它们的药学上可接受的盐、它们的制备工艺和含有它们的药物组合物。本发明还涉及制备此类化合物的中间体及其制备工艺。