2-hydroxy-3-(N-methylhexadecylammonio)propane-sulfonate | 1414932-93-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: 2-hydroxy-3-(N-methylhexadecylammonio)propane-sulfonate
• 英文别名: 3-[Hexadecyl(methyl)azaniumyl]-2-hydroxypropane-1-sulfonate
• CAS: 1414932-93-6
• 化学式: C₂₀H₄₃NO₄S
• 分子量: 393.632
• InChiKey: QUJWNRVPOFWWHB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  26
• 可旋转键数：
  19
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  86.2
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• [EN] OXYGENATED AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID, PHOSPHONIC ACID AND CARBOXYLIC ACID DERIVATIVES AND THEIR MEDICAL USE<br/>[FR] DÉRIVÉS D'ACIDE SULFONIQUE, D'ACIDE PHOSPHONIQUE ET D'ACIDE CARBOXYLIQUE CONTENANT DES GROUPES AMINO OU AMMONIUM OXYGÉNÉS, ET LEUR UTILISATION MÉDICALE
  申请人：JADO TECHNOLOGIES GMBH

  公开号：WO2012160186A1

  公开（公告）日：2012-11-29

  The present invention relates to oxygenated amino or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives, in particular the compounds of formula 1, 2, 3, 4, 5 or 6, and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.

  本发明涉及含氧氨基或铵基磺酸、膦酸和羧酸衍生物，特别是式1、2、3、4、5或6的化合物，以及它们在医学上的用途，包括它们在治疗、预防或改善炎症、自身免疫和/或过敏性疾病，或增生性、肿瘤性或异型增生性疾病或紊乱中的应用。
• OXYGENATED AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID, PHOSPHONIC ACID AND CARBOXYLIC ACID DERIVATIVES AND THEIR MEDICAL USE
  申请人：Schlechtingen Georg

  公开号：US20150284320A1

  公开（公告）日：2015-10-08

  The present invention relates to oxygenated amino or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives, in particular the compounds of formula 1, 2, 3, 4, 5 or 6, and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.

  本发明涉及含氧氨基或铵基的磺酸衍生物、膦酸衍生物和羧酸衍生物，特别是公式1、2、3、4、5或6的化合物及其医药用途，包括它们在治疗、预防或改善炎症、自身免疫和/或过敏性疾病，或增生性、肿瘤性或畸形性疾病或障碍中的应用。
• Oxygenated amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use
  申请人：GRI BIO, INC.

  公开号：US10815195B2

  公开（公告）日：2020-10-27

  The present invention relates to oxygenated amino or ammonium-containing sulfonic acid, phosphoric acid and carboxylic acid derivatives, in particular the compounds of formula 1, 2, 3, 4, 5 or 6, and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.

  本发明涉及含氧氨基或含铵磺酸、磷酸和羧酸衍生物，特别是式 1、2、3、4、5 或 6 的化合物及其医疗用途，包括用于治疗、预防或改善炎症性、自身免疫性和/或过敏性疾病，或增生性、肿瘤性或发育不良性疾病或紊乱。
• OXYGENATED AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID DERIVATIVES AND THEIR MEDICAL USE
  申请人：GRI Bio, Inc.

  公开号：EP2809648B1

  公开（公告）日：2019-04-03
• PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS
  申请人：GRI Bio, Inc.

  公开号：EP3229811B1

  公开（公告）日：2021-02-24