3-tert-butyldimethylsilyloxy-2’,3’,2”,3”-tetramethoxy-1,2:5,6-dibenzocyclocta-1,5,7-triene | 1389327-60-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3-tert-butyldimethylsilyloxy-2’,3’,2”,3”-tetramethoxy-1,2:5,6-dibenzocyclocta-1,5,7-triene
• CAS: 1389327-60-9
• 化学式: C₂₆H₃₆O₅Si
• 分子量: 456.654
• InChiKey: LNMJDCVUQWTRRG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.51
• 重原子数：
  32.0
• 可旋转键数：
  6.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  46.15
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  3-tert-butyldimethylsilyloxy-2’,3’,2”,3”-tetramethoxy-1,2:5,6-dibenzocyclocta-1,5,7-triene 在 N-甲基哌嗪 、 potassium tert-butylate 、 四丁基氟化铵 、 溴 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 18.83h， 生成 3-hydroxy-2’,3’,2”,3”-tetramethoxy-7,8-didehydro-1,2:5,6-dibenzocyclocta-1,5,7-triene
  参考文献：
  名称：

  High Spatiotemporal Control of Spontaneous Reactions Using Ultrasound-Triggered Composite Droplets

  摘要：

  Achieving high spatial and temporal control over a spontaneous reaction is a particularly challenging task with potential breakthroughs in various fields of research including surface patterning and drug delivery. We report here an exceptionally effective method that allows attaining such control. This method relies on a remotely triggered ultrasound-induced release of a reactant encapsulated in a composite microdroplet of liquid perfluorohexane. More specifically, the demonstration was achieved by locally applying a focused 2.25 MHz transducer onto a microfluidic channel in which were injected composite microdroplets containing a solution of an azidocoumarin and an external flow containing a reactive alkyne.

  DOI：

  10.1021/ja5019354
• 作为产物：
  描述：

  2',3',2'',3''-tetramethoxy-2,3:6,7-dibenzo-9-oxabicyclo<3.3.1>nona-2,6-diene 在 咪唑 、 正丁基锂 、 叔丁基二甲硅基三氟甲磺酸酯 、 甲基锂 、 1,7-菲啰啉 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 反应 20.0h， 生成 3-tert-butyldimethylsilyloxy-2’,3’,2”,3”-tetramethoxy-1,2:5,6-dibenzocyclocta-1,5,7-triene
  参考文献：
  名称：

  High Spatiotemporal Control of Spontaneous Reactions Using Ultrasound-Triggered Composite Droplets

  摘要：

  Achieving high spatial and temporal control over a spontaneous reaction is a particularly challenging task with potential breakthroughs in various fields of research including surface patterning and drug delivery. We report here an exceptionally effective method that allows attaining such control. This method relies on a remotely triggered ultrasound-induced release of a reactant encapsulated in a composite microdroplet of liquid perfluorohexane. More specifically, the demonstration was achieved by locally applying a focused 2.25 MHz transducer onto a microfluidic channel in which were injected composite microdroplets containing a solution of an azidocoumarin and an external flow containing a reactive alkyne.

  DOI：

  10.1021/ja5019354