5-Acetoxy-2-methyl-furan | 65748-93-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: 5-Acetoxy-2-methyl-furan
• 英文别名: 2-acetoxy-5-methyl-furan；(5-Methylfuran-2-yl) acetate
• CAS: 65748-93-8
• 化学式: C₇H₈O₃
• 分子量: 140.139
• InChiKey: UTXGOYVSQBQRAI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  39.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-甲基呋喃 、 丙烯酸甲酯（MA） 、 醋酸钯 以5%的产率得到
  参考文献：
  名称：

  MARUYAMA, OSAMU;FUJIWARA, YUZO;TANIGUCHI, HIROSHI, BULL. CHEM. SOC. JAP., 1981, 54, N 9, 2851-2852

  摘要：

  DOI：

文献信息

• [EN] OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS<br/>[FR] DERIVES D'OXAZOLIDINONE UTILISES EN TANT QU'ANTIMICROBIENS
  申请人：RANBAXY LAB LTD

  公开号：WO2002006278A1

  公开（公告）日：2002-01-24

  The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharma-ceutical compositions containing the compounds of the present invention as anti-microbials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacterioides spp. and Clostridia spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.

  本发明涉及某些取代苯基噁唑烷酮及其合成方法。本发明还涉及以本发明化合物作为抗微生物药物的药物组合物。这些化合物是有用的抗微生物剂，对多种人类和兽医病原体有效，包括革兰氏阳性需氧菌，如多重耐药葡萄球菌、链球菌和肠球菌，以及厌氧菌，如拟杆菌属和梭菌属物种，以及酸性快速生长菌，如结核分枝杆菌、鸟型分枝杆菌和分枝杆菌属物种。
• OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS
  申请人：RANBAXY LABORATORIES, LTD.

  公开号：EP1303511A1

  公开（公告）日：2003-04-23
• US4214092A
  申请人：——

  公开号：US4214092A

  公开（公告）日：1980-07-22
• [EN] OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS<br/>[FR] DERIVES D'OXAZOLIDINONE COMME ANTIMICROBIENS
  申请人：RANBAXY LAB LTD

  公开号：WO2003007870A2

  公开（公告）日：2003-01-30

  The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharma-ceutical compositions containing the compounds of the present invention as anti-microbials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacterioides spp. and Clostridia spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.