4-(4-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yloxy)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-7-yl)benzeneamine | 1384951-64-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 4-(4-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yloxy)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-7-yl)benzeneamine
• 英文别名: 4-(4-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yloxy)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-7-yl)benzenamine；4-[4-[1-(5-Ethylpyrimidin-2-yl)piperidin-4-yl]oxy-5-methylpyrrolo[3,2-d]pyrimidin-7-yl]aniline
• CAS: 1384951-64-7
• 化学式: C₂₄H₂₇N₇O
• 分子量: 429.525
• InChiKey: SHOKABGEEIPYJE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  32
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  95
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• NEW BICYCLIC COMPOUND FOR MODULATING G PROTEIN-COUPLED RECEPTORS
  申请人：Son Jung Beom

  公开号：US20130274268A1

  公开（公告）日：2013-10-17

  The present invention relates to a bicyclic compound for modulating G protein-coupled receptors. The inventive compound provides preventing or treating a disease associated with the modulation of G protein-coupled receptors, particularly GPR119 G protein-coupled receptors.

  本发明涉及一种用于调节G蛋白偶联受体的双环化合物。该创新化合物可用于预防或治疗与调节G蛋白偶联受体相关的疾病，特别是GPR119 G蛋白偶联受体。
• US8853213B2
  申请人：——

  公开号：US8853213B2

  公开（公告）日：2014-10-07
• [EN] NEW BICYCLIC COMPOUND FOR MODULATING G PROTEIN-COUPLED RECEPTORS<br/>[FR] NOUVEAU COMPOSÉ BICYCLIQUE POUR LA MODULATION DE RÉCEPTEURS COUPLÉS À LA PROTÉINE G
  申请人：HANMI PHARM IND CO LTD

  公开号：WO2012093809A2

  公开（公告）日：2012-07-12

  The present invention relates to a bicyclic compound for modulating G protein-coupled receptors. The inventive compound provides preventing or treating a disease associated with the modulation of G protein-coupled receptors, particularly GPR119 G protein-coupled receptors.