(3-Methoxyphenyl)-(2-phenyldiazenylphenyl)methanone | 1421276-25-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (3-Methoxyphenyl)-(2-phenyldiazenylphenyl)methanone
• 英文别名: (3-methoxyphenyl)-(2-phenyldiazenylphenyl)methanone
• CAS: 1421276-25-6
• 化学式: C₂₀H₁₆N₂O₂
• 分子量: 316.359
• InChiKey: GLWQIECGHGLTCF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  51
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (3-Methoxyphenyl)-(2-phenyldiazenylphenyl)methanone 在 甲醇 、 氯化铵 、 锌 作用下， 反应 0.08h， 以99%的产率得到3-(3-methoxyphenyl)-2-phenyl-2H-indazole
  参考文献：
  名称：

  Direct Access to Acylated Azobenzenes via Pd-Catalyzed C–H Functionalization and Further Transformation into an Indazole Backbone

  摘要：

  Azobenzenes were readily acylated at the 2-position through a Pd-catalyzed C-H functionalization from simple aromatic azo compounds and aldehydes in good yields. The obtained acylated azobenzenes could be efficiently converted into the corresponding indazole derivatives in nearly quantitative yields.

  DOI：

  10.1021/ol303434n
• 作为产物：
  描述：

  苯胺 在 叔丁基过氧化氢 、 palladium diacetate 、 copper(I) bromide 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 12.0h， 生成 (3-Methoxyphenyl)-(2-phenyldiazenylphenyl)methanone
  参考文献：
  名称：

  Direct Access to Acylated Azobenzenes via Pd-Catalyzed C–H Functionalization and Further Transformation into an Indazole Backbone

  摘要：

  Azobenzenes were readily acylated at the 2-position through a Pd-catalyzed C-H functionalization from simple aromatic azo compounds and aldehydes in good yields. The obtained acylated azobenzenes could be efficiently converted into the corresponding indazole derivatives in nearly quantitative yields.

  DOI：

  10.1021/ol303434n

文献信息

• Direct Access to Acylated Azobenzenes via Pd-Catalyzed C–H Functionalization and Further Transformation into an Indazole Backbone
  作者：Hongji Li、Pinhua Li、Lei Wang

  DOI：10.1021/ol303434n

  日期：2013.2.1

  Azobenzenes were readily acylated at the 2-position through a Pd-catalyzed C-H functionalization from simple aromatic azo compounds and aldehydes in good yields. The obtained acylated azobenzenes could be efficiently converted into the corresponding indazole derivatives in nearly quantitative yields.