2-(4-ethoxyphenyl)-6-(2H-tetrazol-5-yl)-1H-benzimidazole | 1620517-90-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 2-(4-ethoxyphenyl)-6-(2H-tetrazol-5-yl)-1H-benzimidazole
• CAS: 1620517-90-9
• 化学式: C₁₆H₁₄N₆O
• 分子量: 306.327
• InChiKey: CTYHTAQFTQUPDD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  92.4
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  5-cyano-2-(4-ethoxyphenyl)-3H-benzimidazole 在 sodium azide 、 silver 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 8.0h， 生成 2-(4-ethoxyphenyl)-6-(2H-tetrazol-5-yl)-1H-benzimidazole
  参考文献：
  名称：

  Efficient heterogeneous silver nanoparticles catalyzed one-pot synthesis of 5-substituted 1H-tetrazoles

  摘要：

  Silver nanoparticles (AgNPs), characterized by TEM, EDX and UV studies were used as an efficient heterogeneous catalyst for the synthesis of 5-substituted 1H-tetrazoles from various nitriles possessing different functional groups in excellent yields. All title compounds were characterized by spectroscopy (H-1 NMR, C-13 NMR and IR) and crystallography. (C) 2014 Published by Elsevier B.V.

  DOI：

  10.1016/j.molcata.2014.05.008

文献信息

• Efficient heterogeneous silver nanoparticles catalyzed one-pot synthesis of 5-substituted 1H-tetrazoles
  作者：Pavnesh Mani、Chiranjeev Sharma、Satyanand Kumar、Satish Kumar Awasthi

  DOI：10.1016/j.molcata.2014.05.008

  日期：2014.10

  Silver nanoparticles (AgNPs), characterized by TEM, EDX and UV studies were used as an efficient heterogeneous catalyst for the synthesis of 5-substituted 1H-tetrazoles from various nitriles possessing different functional groups in excellent yields. All title compounds were characterized by spectroscopy (H-1 NMR, C-13 NMR and IR) and crystallography. (C) 2014 Published by Elsevier B.V.