2-[7-(Diethylamino)-2-oxochromen-3-yl]-1,3-oxazole-5-carbaldehyde | 1334431-91-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 2-[7-(Diethylamino)-2-oxochromen-3-yl]-1,3-oxazole-5-carbaldehyde
• 英文别名: 2-[7-(diethylamino)-2-oxochromen-3-yl]-1,3-oxazole-5-carbaldehyde
• CAS: 1334431-91-2
• 化学式: C₁₇H₁₆N₂O₄
• 分子量: 312.325
• InChiKey: TVHAHUSDBFNDFA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  72.6
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  sodium 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate 在 草酰氯 、 mercury(II) trifluoroacetate 、 三乙胺 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 生成 2-[7-(Diethylamino)-2-oxochromen-3-yl]-1,3-oxazole-5-carbaldehyde
  参考文献：
  名称：

  Ratiometric fluorescence chemodosimeter for mercuric ions through the Hg(II)-mediated propargyl amide to oxazole transformation

  摘要：

  A coumarin-based alkyne was developed as a fluorescent chemodosimeter for the selective detection of mercuric ion. The probe showed a highly selective and ratiometric response toward Hg(II) ion over other metal ions with a micromolar level of limit of detection. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.07.019

文献信息

• Ratiometric fluorescence chemodosimeter for mercuric ions through the Hg(II)-mediated propargyl amide to oxazole transformation
  作者：Heejin Lee、Hae-Jo Kim

  DOI：10.1016/j.tetlet.2011.07.019

  日期：2011.9

  A coumarin-based alkyne was developed as a fluorescent chemodosimeter for the selective detection of mercuric ion. The probe showed a highly selective and ratiometric response toward Hg(II) ion over other metal ions with a micromolar level of limit of detection. (C) 2011 Elsevier Ltd. All rights reserved.