| 1575823-39-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• CAS: 1575823-39-0
• 化学式: C₁₈H₁₆O₄
• 分子量: 296.323
• InChiKey: XFLILQYCPPDOIB-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 solid supported silica sulfuric acid 作用下， 以 neat (no solvent) 为溶剂， 反应 3.0h， 以87%的产率得到5-isopropyl-3H,3'H-spiro[benzofuran-2,1'-isobenzofuran]-3,3'-dione
  参考文献：
  名称：

  Silica sulfuric acid: an efficient reusable heterogeneous solid support for the synthesis of 3H,3′H-spiro[benzofuran-2,1′isobenzofuran]-3,3′-diones under solvent-free condition

  摘要：

  A highly efficient protocol for the library synthesis of biologically important 3H,3'H-spiro[benzofuran-2,1'isobenzofuran]-3,3'-diones has been developed by employing silica sulfuric acid (SSA) as solid acid support under solvent-free condition. The dual characteristics of SSA, as an activating agent as well as oxidizing agent, have been well exposed in these syntheses. The intrinsic advantages of the methodology are the use of solvent-free reaction condition without using any toxic reagents or metal catalyst, operational simplicity, recyclability of the solid support, good availability of the starting materials, and excellent yields which make the method attractive, economic, and 'benign by design'. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.01.109