[3-[2-(Furan-3-ylmethyl)-1,3-dithian-2-yl]cyclopenten-1-yl]oxy-tri(propan-2-yl)silane | 1280709-72-9

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫代缩醛
• 英文名称: [3-[2-(Furan-3-ylmethyl)-1,3-dithian-2-yl]cyclopenten-1-yl]oxy-tri(propan-2-yl)silane
• 英文别名: [3-[2-(furan-3-ylmethyl)-1,3-dithian-2-yl]cyclopenten-1-yl]oxy-tri(propan-2-yl)silane
• CAS: 1280709-72-9
• 化学式: C₂₃H₃₈O₂S₂Si
• 分子量: 438.771
• InChiKey: NYLIXESOCBYQRS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.87
• 重原子数：
  28
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  73
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  [3-[2-(Furan-3-ylmethyl)-1,3-dithian-2-yl]cyclopenten-1-yl]oxy-tri(propan-2-yl)silane 在 2,6-二甲基吡啶 、 lithium perchlorate 、 二异丁基氢化铝 作用下， 以 甲醇 、 二氯甲烷 、 水 为溶剂， 反应 0.5h， 生成
  参考文献：
  名称：

  Anodic Coupling Reactions: Exploring the Generality of Curtin−Hammett Controlled Reactions

  摘要：

  Intramolecular anodic olefin coupling reactions can be compatible with the presence of dithioketal protecting groups even though the dithioketal oxidizes at a lower potential than either of the groups participating in the cyclization. In such cases, product formation is controlled by the Curtin-Hammett Principle. In this study, the generality of such reactions is examined along with the use of alternative reaction conditions to suppress unwanted side reactions.

  DOI：

  10.1021/ol200182f
• 作为产物：
  描述：

  3-溴甲基呋喃 在 六甲基磷酰三胺 、 正丁基锂 、 叔丁基锂 作用下， 以 四氢呋喃 为溶剂， 反应 8.5h， 生成 [3-[2-(Furan-3-ylmethyl)-1,3-dithian-2-yl]cyclopenten-1-yl]oxy-tri(propan-2-yl)silane
  参考文献：
  名称：

  Anodic Coupling Reactions: Exploring the Generality of Curtin−Hammett Controlled Reactions

  摘要：

  Intramolecular anodic olefin coupling reactions can be compatible with the presence of dithioketal protecting groups even though the dithioketal oxidizes at a lower potential than either of the groups participating in the cyclization. In such cases, product formation is controlled by the Curtin-Hammett Principle. In this study, the generality of such reactions is examined along with the use of alternative reaction conditions to suppress unwanted side reactions.

  DOI：

  10.1021/ol200182f

文献信息

• Anodic Coupling Reactions: Exploring the Generality of Curtin−Hammett Controlled Reactions
  作者：Alison Redden、Kevin D. Moeller

  DOI：10.1021/ol200182f

  日期：2011.4.1

  Intramolecular anodic olefin coupling reactions can be compatible with the presence of dithioketal protecting groups even though the dithioketal oxidizes at a lower potential than either of the groups participating in the cyclization. In such cases, product formation is controlled by the Curtin-Hammett Principle. In this study, the generality of such reactions is examined along with the use of alternative reaction conditions to suppress unwanted side reactions.