丙二醇单肉豆蔻基醚乙酸酯 | 135326-54-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 丙二醇单肉豆蔻基醚乙酸酯
• 中文别名: (十四烷氧基)丙醇乙酸酯；丙二醇单肉豆蔻醇醚乙酸酯
• 英文名称: propylene glycol myristyl ether acetate
• 英文别名: Hetester PMA；1-tetradecoxypropan-2-yl acetate
• CAS: 135326-54-4
• 化学式: C₁₉H₃₈O₃
• 分子量: 314.509
• InChiKey: PCRBTNZNEYJDCH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  22
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• SMALL MOLECULE CMKLR1 ANTAGONISTS IN INFLAMMATORY DISEASE
  申请人：The Board of Trustees of the Leland Stanford Junior University

  公开号：US20200345661A1

  公开（公告）日：2020-11-05

  α-NETA analogs are provided for the treatment of inflammatory disease.

  α-NETA类似物用于治疗炎症性疾病。
• PREPARATION COMPRISING CHROMAN-2-ONE DERIVATIVES
  申请人：Mujica-Fernaud Teresa

  公开号：US20100291009A1

  公开（公告）日：2010-11-18

  The invention relates to preparations comprising at least one compound of the formula (I), where the substituents R 1 to R 4 have a meaning indicated in claim 1 , and salts and solvates thereof, and to the use thereof and selected compounds of the formula (I).

  该发明涉及包含至少一种式(I)化合物的制剂，其中取代基R1至R4具有权利要求1中指示的含义，以及其盐和溶剂合物，以及其用途和选择的式(I)化合物。
• Lip treatment composition
  申请人：UNILEVER PLC

  公开号：EP0549267A1

  公开（公告）日：1993-06-30

  A lip-treatment composition for topical application to the lips comprising a base comprising oil, water and a structurant, and at least one active component active with regard to the lips, gums, teeth, throat, or oral mucosa.

  一种用于涂抹在嘴唇上的唇部护理组合物，包括基础成分，其中包括油、水和一种结构剂，以及至少一种对嘴唇、牙龈、牙齿、喉咙或口腔粘膜具有活性作用的活性成分。
• Compositions and methods to treat skin diseases characterized by cellular proliferation and angiogenesis
  申请人：Sherris David

  公开号：US20060257337A1

  公开（公告）日：2006-11-16

  Described herein are compositions and methods for preventing and/or treating skin diseases including, but not limited to, psoriasis and atopic dermatitis as well as providing anti-aging benefits which results in reduced appearance of wrinkles and aged skin, improved skin color, treatment of photodamaged skin, improvement in skin's radiance and clarity and finish, and an overall healthy and youthful appearance of the skin, involving aberrant angiogenesis and hyperplasia employing one or more benzo[c]chromen-6-one derivatives.

  本文描述了一种预防和/或治疗皮肤疾病的组合物和方法，包括但不限于银屑病和特应性皮炎，以及提供抗衰老益处，减少皱纹和老化皮肤的出现，改善皮肤颜色，治疗光损伤皮肤，改善皮肤的光泽和清晰度以及完美度，以及使皮肤呈现整体健康和年轻外观，涉及使用一个或多个苯并[c]色素-6-酮衍生物的异常血管生成和增生。
• USE OF CHROMEN-4-ONE DERIVATIVES
  申请人：Carola Christophe

  公开号：US20090209637A1

  公开（公告）日：2009-08-20

  The invention relates to the use of chromen-4-one derivatives of the formula I where R 1 and R 2 may be identical or different and are selected from H, —C(═O)—R 7 , —C(═O)—OR 7 , alkyl groups, alkenyl groups, hydroxyalkyl groups and/or cycloalkyl groups and/or cycloalkenyl groups, R 3 is H or alkyl groups, R 4 is H or OR 8 , R 5 and R 6 are selected from —H, —OH, alkyl groups, alkenyl groups and hydroxyalkyl groups, and R 7 is H, alkyl groups, a polyhydroxyl compound, such as, preferably, an ascorbic acid radical or glycosidic radicals, and R 8 is H or alkyl groups, where at least two of the substituents R 1 , R 2 and R 4 -R 6 are different from H or at least one substituent from R 1 and R 2 is —C(═O)—R 7 or —C(═O)—OR 7 , to prevent, reduce or combat signs of cellulite and/or reduce localized fatty excesses.

  该发明涉及使用式I的香豆素-4-酮衍生物，其中R1和R2可以相同也可以不同，选择自H、—C(═O)—R7、—C(═O)—OR7、烷基基团、烯基基团、羟基烷基基团和/或环烷基基团和/或环烯基基团，R3为H或烷基基团，R4为H或OR8，R5和R6选择自—H、—OH、烷基基团、烯基基团和羟基烷基基团，R7为H、烷基基团、多羟基化合物，例如，优选为抗坏血酸基团或糖苷基团，R8为H或烷基基团，其中至少两个取代基R1、R2和R4-R6与H不同，或者R1和R2中至少一个取代基为—C(═O)—R7或—C(═O)—OR7，以预防、减少或对抗橘皮组织的迹象和/或减少局部脂肪过剩。