2,3,3-Trimethyl-1-pyrrolin | 3433-71-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯啉
• 英文名称: 2,3,3-Trimethyl-1-pyrrolin
• 英文别名: 4,4,5-trimethyl-3,4-dihydro-2H-pyrrole；Trimethyl-1-pyrroline；4,4,5-trimethyl-2,3-dihydropyrrole
• CAS: 3433-71-4
• 化学式: C₇H₁₃N
• 分子量: 111.187
• InChiKey: NJGXRPJTTPFGJA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• PHARMACEUTICAL COMPOUNDS
  申请人：Lazzari Paolo

  公开号：US20100105896A1

  公开（公告）日：2010-04-29

  Pyrazole derivatives of the following formula (I), having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein: R is a group selected from C 1 -C 10 alkyl; aryl, arylalkyl or arylalkenyl, not substituted or having from one to four substituents, equal to or different from each other; A is a group selected from the following: an ether group of formula —(CH 2 )—O—(CH 2 ) v —R″ wherein v is equal to 1 or 2; R″ is as defined in the present application; a ketone group of formula —C(O)—Z′, wherein Z′ is as defined in the present application; a substituent having an hydroxyl function of formula —CH(OH)—Z′, being as defined in the present application; an amide substituent of formula —C(O)—NH-T′, T′ being as defined in the present application; B is a group as defined in the present application; D is an heteroaryl optionally substituted.