2-[2-Hydroxy-3-(hydroxymethyl)phenyl]ethyl prop-2-enoate | 1234791-11-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[2-Hydroxy-3-(hydroxymethyl)phenyl]ethyl prop-2-enoate
• 英文别名: 2-[2-hydroxy-3-(hydroxymethyl)phenyl]ethyl prop-2-enoate
• CAS: 1234791-11-7
• 化学式: C₁₂H₁₄O₄
• 分子量: 222.241
• InChiKey: IWDAYNKADJEWRS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-[2-Hydroxy-3-(hydroxymethyl)phenyl]ethyl prop-2-enoate 在 sodium periodate 作用下， 以 水 、 乙腈 为溶剂， 生成
  参考文献：
  名称：

  A tandem oxidative dearomatization/intramolecular Diels–Alder reaction: a short and efficient entry into tricyclic system of maoecrystal V

  摘要：

  A short and efficient route to tricyclic ring system containing bridged bicyclo[2.2.2]octanone annulated with a lactone ring present in the maoecrystal is described. In-situ generation of spiroepoxycyclohexa-2,4-dienone and intramolecular cycloaddition are the key features of our approach. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.04.082
• 作为产物：
  描述：

  在 盐酸 作用下， 以 四氢呋喃 、 水 为溶剂， 以91.8%的产率得到2-[2-Hydroxy-3-(hydroxymethyl)phenyl]ethyl prop-2-enoate
  参考文献：
  名称：

  A tandem oxidative dearomatization/intramolecular Diels–Alder reaction: a short and efficient entry into tricyclic system of maoecrystal V

  摘要：

  A short and efficient route to tricyclic ring system containing bridged bicyclo[2.2.2]octanone annulated with a lactone ring present in the maoecrystal is described. In-situ generation of spiroepoxycyclohexa-2,4-dienone and intramolecular cycloaddition are the key features of our approach. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.04.082

文献信息

• A tandem oxidative dearomatization/intramolecular Diels–Alder reaction: a short and efficient entry into tricyclic system of maoecrystal V
  作者：Vishwakarma Singh、Pravin Bhalerao、Shaikh M. Mobin

  DOI：10.1016/j.tetlet.2010.04.082

  日期：2010.6

  A short and efficient route to tricyclic ring system containing bridged bicyclo[2.2.2]octanone annulated with a lactone ring present in the maoecrystal is described. In-situ generation of spiroepoxycyclohexa-2,4-dienone and intramolecular cycloaddition are the key features of our approach. (C) 2010 Elsevier Ltd. All rights reserved.