α-OH-Cyclohexylmethanesulfonate, S-Benzylthiuroniumsulfonate | 93152-43-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: α-OH-Cyclohexylmethanesulfonate, S-Benzylthiuroniumsulfonate
• 英文别名: Cyclohexyl(hydroxy)methanesulfonic acid
• CAS: 93152-43-3
• 化学式: C₇H₁₄O₄S
• 分子量: 194.252
• InChiKey: BSTKTZDZFWWUER-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  83
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] NOVEL PROCESS FOR PREPARATION OF GLUCOCORTICOID STEROIDS<br/>[FR] NOUVEAU PROCÉDÉ DE PRÉPARATION DE STÉROÏDES DE TYPE GLUCOCORTICOÏDE
  申请人：CORAL DRUGS PVT LTD

  公开号：WO2016120891A1

  公开（公告）日：2016-08-04

  The present invention discloses a process for the preparation of 16, 17-acetals of pregnane derivatives having formula (I) wherein each substituent is independently selected from; R1 is H or CH3; R2 is C1-C6 linear or branched alkyl, alkynyl group or cycloalkyl group; aryl or heteroaryl group; or R1 and R2 combine to form saturated, unsaturated C3-C6 cyclic or heterocyclic ring; R3 and R4 are same or different and each independently represents H or halogen; R5 is -OH or –OCOR wherein R represents H or C1-C6 linear, branched or cyclic alkyl group that may be substituted.

  本发明揭示了一种制备16,17-孕烷衍生物的16,17-缩醛的方法，其具有式(I)的结构，其中每个取代基独立地选择自; R1为H或CH3; R2为C1-C6直链或支链烷基，炔基或环烷基; 芳基或杂环芳基; 或R1和R2结合形成饱和的、不饱和的C3-C6环或杂环环; R3和R4相同或不同，每个独立地表示H或卤素; R5为-OH或-OCOR，其中R表示H或C1-C6直链、支链或环烷基，可能被取代。
• NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES
  申请人：Mani S. Neelakandha

  公开号：US20070129351A1

  公开（公告）日：2007-06-07

  The present invention is directed to novel processes for the preparation of cyclopropyl-amide derivatives, useful for the treatment of disorders and conditions mediated by the histamine receptor.

  本发明涉及一种新型的环丙基酰胺衍生物制备方法，用于治疗由组胺受体介导的疾病和病状。
• NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES
  申请人：Mani S. Neelakandha

  公开号：US20070197508A1

  公开（公告）日：2007-08-23

  The present invention is directed to novel processes for the preparation of substituted piperazinyl and diazepanyl benzamides, useful for the treatment of disorders and conditions mediated by the histamine receptor.

  本发明涉及一种新型制备取代哌嗪基和二氮杂环巴豆酰胺的方法，可用于治疗组织胺受体介导的疾病和病况。
• NOVEL PROCESS FOR PREPARATION OF GLUCOCORTICOID STEROIDS
  申请人：Coral Drugs Pvt. Ltd.

  公开号：US20180002372A1

  公开（公告）日：2018-01-04

  The present invention discloses a process for the preparation of 16, 17-acetals of pregnane derivatives having formula I wherein each substituent is independently selected from; R 1 is H or CH 3 ; R 2 is C 1 -C 6 linear or branched alkyl, alkynyl group or cycloalkyl group; aryl or heteroaryl group; or R 1 and R 2 combine to form saturated, unsaturated C 3 -C 6 cyclic or heterocyclic ring; R 3 and R 4 are same or different and each independently represents H or halogen; R 5 is —OH or —OCOR wherein R represents H or C 1 -C 6 linear, branched or cyclic alkyl group that may be substituted.
• US7728129B2
  申请人：——

  公开号：US7728129B2

  公开（公告）日：2010-06-01