cis-4'-methoxy-4-stilbazole | 6043-46-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: cis-4'-methoxy-4-stilbazole
• 英文别名: cis-4'-Methoxy-4-stilbazol；(Z)-4-(4-Methoxystyryl)pyridine；4-[(Z)-2-(4-methoxyphenyl)ethenyl]pyridine
• CAS: 6043-46-5
• 化学式: C₁₄H₁₃NO
• 分子量: 211.263
• InChiKey: YOTHHWBAADYJST-IHWYPQMZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  22.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  cis-4'-methoxy-4-stilbazole 在 碘 作用下， 以 四氯化碳 为溶剂， 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Mancini, Vittorio; Passini, Paolo; Santini, Sergio, Journal of the Chemical Society. Perkin transactions II, 1980, p. 463 - 466

  摘要：

  DOI：
• 作为产物：
  描述：

  (4-甲氧基苄基)三苯基氯化膦 在 正丁基锂 作用下， 以 正己烷 、 苯 为溶剂， 反应 0.5h， 生成 cis-4'-methoxy-4-stilbazole
  参考文献：
  名称：

  一系列含席夫碱的tri烷基亚炔基羰基簇的合成，结构表征和溶剂变色研究

  摘要：

  一系列新的席夫含碱triosmium次烷基羰基簇[O的3（μ-H）2（CO）9（μ 3 -数控5 ħ 4 CHNC 6 ħ 4 R）]（R = H，NME 2， SMe，CMe 3，NH 2，Br，Cl，OC n H 2 n +1，n = 1、6、7或9）是通过[Os 3（μ-H）3（CO）9（ μ 3-CCl）]，在室温下存在十倍过量的席夫碱配体NC 5 H 4 CH = NC 6 H 4 R的情况下，用一当量的1,8-二氮杂双环[5.4.0]十一碳-7-烯温度。还使用类似的去质子化方法合成了在顶部碳中心带有4'-甲氧基-4-苯乙烯基唑或4-（4-硝基苄基）吡啶部分的类似的羰基tri鎓羰基簇。所选配合物的分子结构已通过X射线晶体学确定。紫外可见光谱表明，这类化合物在有机介质中显示出显着的负溶剂变色作用。

  DOI：

  10.1016/s0022-328x(99)00091-1

文献信息

• Rationally Designed Pincer-Type Heck Catalysts Bearing Aminophosphine Substituents: Pd^IVIntermediates and Palladium Nanoparticles
  作者：Jeanne L. Bolliger、Olivier Blacque、Christian M. Frech

  DOI：10.1002/chem.200800441

  日期：2008.9.8

  catalytic cycle of the Heck reaction, their general existence as reactive intermediates (for example, in other reactions) cannot be excluded. On the contrary, they were shown to be thermally accessible. Compounds 1 and 2 show a smooth halide exchange with bromobenzene to yield their bromo derivatives in DMF at 100 degrees C. Experimental observations revealed that the halide exchange most probably proceeded

  氨基膦基钳形配合物[C6H3-2,6-（XP（哌啶基）2）2Pd（Cl）]（X = NH 1; X = O 2）可以很容易地由廉价的起始原料通过依次添加1,1在“一锅”中，在N 2下，将'，1''-膦三基三哌啶和1,3-二氨基苯或间苯二酚制得[Pd（cod）（Cl）2]（cod =环辛二烯）在甲苯中的溶液。事实证明，化合物1和2是出色的Heck催化剂，可以在很短的反应时间和较低的催化剂负载量下，在140℃下将数种电子失活和空间位阻的芳基溴化物与各种烯烃作为偶联伴侣进行定量偶联。升高的反应温度还使得在仅0.01mol％的催化剂存在下，烯烃能够与电子失活的和位阻的芳基氯有效地偶联。进行的机理研究排除了均相的Pd 0配合物是1和2的催化活性形式。另一方面，钯纳米颗粒参与催化循环得到了有力的实验支持。即使衍生自1（和2）的钳型Pd IV中间体不参与Heck反应的催化循环，也不能排除它们作为反应性中
• Role of Cation−π Interactions in the Photodimerization of <i>trans</i>-4-Styrylpyridines
  作者：Shinji Yamada、Naoko Uematsu、Kaori Yamashita

  DOI：10.1021/ja074874y

  日期：2007.10.1

  In order to explore the contribution of the cation-pi interaction in the photocyclodimerization of styrylpyridines, the effects of the acid concentration and the substituent on the aryl ring on the product distribution were investigated. The structures of the product dimers were clarified by X-ray crystallographic analysis. In addition, the X-ray packing structures of trans -4-styrylpyridine (1) and its HCl salt were compared. On increasing the acid amount, the yield of the syn-HT dimer significantly increased, whereas that of the cis-isomer decreased. The substituent on the aromatic ring had a significant effect on the product distribution. Irradiation of the substrate styrylpyridine bearing a CH group resulted in much lower selectivity, whereas the photolysis of the substrate having a MeO group resulted in a syn-HT dimer in 95% selectivity. Comparison of the X-ray packing structures of la and 1a center dot HCI clarified the significant differences between them. The molecules of 1a center dot HCl are packed alternately in antiparallel alignment in a face-to-face manner, the distance of which is 3.295 A, strongly suggesting the existence of an intermolecular cation-pi interaction. On the other hand, no such interaction was observed in la. These results lead to a conclusion that pyridinium-pi interactions govern the orientation of the trans-styrylpyridinium in solution, the irradiation of which would result in the selective formation of the syn-HT dimer.
• HAROUTOUNIAN, SERKOS A.;KATZENELLENBOGEN, JOHN A., PHOTOCHEM. AND PHOTOBIOL., 47,(1988) N 4, 503-516
  作者：HAROUTOUNIAN, SERKOS A.、KATZENELLENBOGEN, JOHN A.

  DOI：——

  日期：——