bis(3,4-Dimethylphenyl) carbohydrazide | 29674-79-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: bis(3,4-Dimethylphenyl) carbohydrazide
• 英文别名: 1,5-Bis-(3,4-dimethylphenyl)carbohydrazid；1,3-Bis[(3,4-dimethylphenyl)amino]urea；1,3-bis(3,4-dimethylanilino)urea
• CAS: 29674-79-1
• 化学式: C₁₇H₂₂N₄O
• 分子量: 298.388
• InChiKey: JUQVTTTYUKLVMC-UHFFFAOYSA-N

物化性质

• 密度：
  1.181±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  65.2
• 氢给体数：
  4
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  bis(3,4-Dimethylphenyl) carbohydrazide 在 三氯化铁 作用下， 以 硫酸 、 丙酮 为溶剂， 以94%的产率得到bis(3,4-dimethylphenyl) carbodiazone
  参考文献：
  名称：

  从芳基取代的碳酰肼制备羰基重氮化合物的简便方法

  摘要：

  摘要 报道了一种制备双（取代苯基）碳重氮化合物（ArN=NCON=NAr）的简单新方法。在酸性介质中，通过芳基取代的卡巴肼与氯化铁氧化合成了九种化合物，收率良好。

  DOI：

  10.1080/00397919808007046

文献信息

• Two-Phase Dehydrogenation of Aryl Substituted Carbazide Compounds
  作者：Yulu Wang、Chengjie Ru、Jianping Li、Hong Wang、Donglan Ma

  DOI：10.1080/00397919408010178

  日期：1994.6

  Abstract Two-phase dehydrogenation, which is a new reaction of aryl substituted carbazide compounds, is described in this paper. Ten new azo compounds were synthesized by the reaction of aryl substituted carbazide compounds with a phenoxyl radical between two phases in good yields.

  摘要 本文描述了芳基取代的卡巴肼化合物的新反应——两相脱氢反应。通过芳基取代的卡巴肼化合物与苯氧基自由基在两相之间以良好的产率反应合成了十种新的偶氮化合物。
• The Application of Ceric Ammonium Nitrate in the Synthesis of Carbodiazones
  作者：Jun-Ping Xiao、Yu-Lu Wang、Xue-Shun Jia、Xiao-Yang Wang、Hong Wang

  DOI：10.1080/00397910008087226

  日期：2000.4

  Abstract The preparation of bisaryl carbodiazone compounds from the aryl substituted carbazides with Ceric Ammonium Nitrate (CAN) has been reported for the first time in excellent yields (80-91%). This method only needs simple instruments and short reaction time. A possible mechanism has been suggested.

  摘要 首次报道了用硝酸铈铵 (CAN) 从芳基取代的卡巴肼制备双芳基碳重氮化合物，收率极好 (80-91%)。这种方法只需要简单的仪器和很短的反应时间。已经提出了一种可能的机制。
• Li, Xiao-Chuan; Wang, Yu-Lu; Wang, Jin-Ye, Journal of Chemical Research - Part S, 2002, # 5, p. 234 - 235
  作者：Li, Xiao-Chuan、Wang, Yu-Lu、Wang, Jin-Ye

  DOI：——

  日期：——
• SELECTIVE AND EFFICIENT OXIDATION OF DIARYL CARBAZIDE TO DIARYL CARBAZONE WITH NaNO₂–ACETIC ANHYDRIDE UNDER MILD CONDITIONS
  作者：Xiao-Chuan Li、Yu-Lu Wang、Jin-Ye Wang

  DOI：10.1081/scc-120014033

  日期：2002.1

  In this paper, ten diaryl carbazide undergo selective and rapid oxidation to the corresponding diaryl carbazone using NaNO2 -acetic anhydride as a novel oxidant under mild conditions for the first time.
• The Synthesis of New Type Bisazo Compounds Using 4-Hydroxy-2,2,6,6-Tetramethyl-l-Piperidinyloxyl as The Phase-Transfer Dehydrogenation Catalyst
  作者：Xiao-Yang Wang、Yu-Lu Wang、Zi-Yi Zhang、Jian-Ping Li、Cai-Lan Wang

  DOI：10.1002/jccs.199800127

  日期：1998.12

  AbstractUsing 4‐hydroxy‐2, 2, 6, 6‐tetramethyl‐l ‐piperidinyloxyl as the phase‐transfer dehydrogenation catalyst to prepare bisazo compounds is reported for the first time. Nine bisaryl carbodiazones were synthesized in high yields under mild conditions. This method was efficient, convenient and rapid. A possible mechanism was suggested by a nitroxide free radical which acted on aryl substituted carbazides to form azo compounds.