1-Cyclopropyl-2,5-dimethyl-1H-pyrrole | 54609-12-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 1-Cyclopropyl-2,5-dimethyl-1H-pyrrole
• 英文别名: 1-Cyclopropyl-2,5-dimethylpyrrole
• CAS: 54609-12-0
• 化学式: C₉H₁₃N
• mdl: MFCD12187123
• 分子量: 135.209
• InChiKey: ZHAYXRUZLFCGLF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.14
• 重原子数：
  10.0
• 可旋转键数：
  1.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.555
• 拓扑面积：
  4.93
• 氢给体数：
  0.0
• 氢受体数：
  0.0

文献信息

• EBNA1 INHIBITORS AND THEIR METHOD OF USE
  申请人：The Wistar Institute Of Anatomy And Biology

  公开号：EP3068758A1

  公开（公告）日：2016-09-21
• [EN] EBNA1 INHIBITORS AND THEIR METHOD OF USE<br/>[FR] INHIBITEURS D'EBNA1 ET LEUR PROCÉDÉ D'UTILISATION
  申请人：WISAR INST OF ANATOMY AND BIOLOGY

  公开号：WO2015073864A1

  公开（公告）日：2015-05-21

  Pharmaceutical compositions of the invention comprise EBNA1 inhibitors useful for the treatment of diseases caused by EBNA1 activity such as cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and rheumatoid arthritis. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by lytic Epstein-Barr Virus (EBV) infection.