4-Acetyl-3-brom-2-nitrothiophen | 35717-23-8

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: 4-Acetyl-3-brom-2-nitrothiophen
• 英文别名: 1-(4-bromo-5-nitro-thiophen-3-yl)-ethanone；1-(4-Bromo-5-nitrothiophen-3-yl)ethanone
• CAS: 35717-23-8
• 化学式: C₆H₄BrNO₃S
• 分子量: 250.073
• InChiKey: DLROUGMBLYSGRO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  91.1
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Anti-Infective Compounds
  申请人：Institut Pasteur Korea

  公开号：US20170121349A1

  公开（公告）日：2017-05-04

  The present invention relates to small molecule compounds having the general formula (I): wherein A is a moiety selected from the group consisting of formulae (A) to (K) and their use in the treatment of bacterial infections, in particular Tuberculosis.
• [EN] [1,2,4]THIADIAZINE 1,1-DIOXIDE COMPOUNDS FOR LOWERING SERUM URIC ACID<br/>[FR] COMPOSÉS DE [1,2,4]THIADIAZINE 1,1-DIOXYDE DESTINÉS À ABAISSER LE NIVEAU D'ACIDE URIQUE SÉRIQUE
  申请人：ANADYS PHARMACEUTICALS INC

  公开号：WO2012170536A1

  公开（公告）日：2012-12-13

  The present invention describes [1,2,4]thiadiazine 1,1-dioxide compounds and pharmaceutically acceptable salts thereof, which are useful in lowering serum uric acid in a patient in need thereof comprising administering to the patient a therapeutically or prophylactically effective amount of a [1,2,4]thiadiazine 1,1- dioxide compound.