2-hexyl 2-cyanoacrylate | 398147-86-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-hexyl 2-cyanoacrylate
• 英文别名: 2-hexyl cyanoacrylate；2-Propenoic acid, 2-cyano-, 1-methylpentyl ester；hexan-2-yl 2-cyanoprop-2-enoate
• CAS: 398147-86-9
• 化学式: C₁₀H₁₅NO₂
• 分子量: 181.235
• InChiKey: RKVIEVIJBJXOFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  50.1
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• METHODS OF TREATING A BLOOD VESSEL
  申请人：Kerber Charles W.

  公开号：US20090137981A1

  公开（公告）日：2009-05-28

  Described herein are methods for treating a blood vessel. In an embodiment, the method of treating a blood vessel comprises providing at least one manipulable tool in a blood vessel, depositing a non-solid polymerizable material into a deposition area of the vessel, wherein the polymerizable liquid hardens over time upon contact with blood in the blood vessel, and altering the shape of the polymerizable material while it hardens by manipulating the tool.

  描述了治疗血管的方法。在一个实施例中，治疗血管的方法包括在血管中提供至少一个可操作的工具，将非固体聚合材料沉积到血管的沉积区，其中聚合液体在与血管中的血液接触后随时间硬化，并通过操作工具在材料硬化时改变其形状。
• SINGLE VIAL FORMULATION FOR MEDICAL GRADE CYANOACRYLATE
  申请人：Kerber Charles W.

  公开号：US20090257976A1

  公开（公告）日：2009-10-15

  Alkyl cyanoacrylate compositions and methods for making those compositions, utilizing high purity monomeric starting materials, formed into more viscous oligomers, and combined with a plasticizer and inhibitor to provide a single-container, storage stable medical cyanoacrylate.

  烷基氰基丙烯酸酯组合物及制备这些组合物的方法，利用高纯度单体起始材料，形成更粘稠的寡聚物，并与增塑剂和抑制剂结合，以提供单容器、储存稳定的医用氰基丙烯酸酯。
• Compositions useful for remodeling body spaces
  申请人：——

  公开号：US20020141969A1

  公开（公告）日：2002-10-03

  A composition comprising of a monomer component comprised of at least one alkyl cyanoacrylate and at least one inhibitor, and a second component comprised of a resultant aggregate structure formed from an alkyl cyanoacrylate monomer, an alkyl esterified fatty acid and an opacificant agent where said composition forms a resultant aggregate structure when said composition contacts an anionic environment. The compositions are useful for filling, occluding, partially filling or partially occluding an unfilled volume or space in a mass in an anionic environment. The composition are also useful for ablating diseased or undesired tissue by cutting off the blood supply to the tissue.

  一种组合物，包括至少一种烷基氰基丙烯酸酯单体组分和至少一种抑制剂的单体组分，以及第二组分，该第二组分包括由烷基氰基丙烯酸酯单体、烷基酯化脂肪酸和不透明剂形成的结果聚集结构，当该组合物接触到阴离子环境时，该组合物形成结果聚集结构。该组合物可用于在阴离子环境中填充、堵塞、部分填充或部分堵塞质量中的未填充体积或空间。该组合物还可用于通过切断组织的血液供应来消融疾病或不需要的组织。
• Composition, reaction product, kit and applicator, especially for use in medicine
  申请人：AESCULAP AG

  公开号：EP2708245A2

  公开（公告）日：2014-03-19

  The invention relates to a composition, especially for use in medicine, comprising a component a) containing cyanoacrylate monomers and an aqueous component b), wherein the composition further comprises an acid and a salt which reacts with the acid to release a gas. The invention further relates to a reaction product obtainable from the composition in the form of a porous and specifically shape-stable foamed structure in particular. The invention further relates to a kit comprising spatially separate from each other an acid component a) and a salt component b) and also to an applicator having a first chamber containing an acid component a) and a second chamber containing a salt component b).

  本发明涉及一种组合物，特别是用于医药的组合物，该组合物包括含有氰基丙烯酸酯单体的成分 a) 和含水成分 b)，其中该组合物还包括一种酸和一种盐，该盐与酸反应释放出一种气体。 本发明还涉及一种可从该组合物中获得的反应产物，其形式尤其为多孔且形状稳定的发泡结构。 本发明还涉及一种试剂盒，该试剂盒包括在空间上相互分离的酸组分 a) 和盐组分 b)，还涉及一种涂抹器，该涂抹器具有一个装有酸组分 a) 的第一腔室和一个装有盐组分 b) 的第二腔室。
• CURABLE TWO-PART ADHESIVE COMPOSITION
  申请人：Bostik SA

  公开号：EP3943521A1

  公开（公告）日：2022-01-26

  The present invention refers to a curable two-part adhesive composition comprising a first part comprising one or more cyanoacrylate monomer(s), one or more (metha)acrylate monomer(s), a per-compound and, optionally, additives to control viscosity and rheology; and a second part comprising: a non-reactive diluent and a transition metal catalyst, and optionally an electron rich initiator for cyanoacrylates. It also relates to a syringe or a cartridge comprising said two-part curable composition, to the use of such composition for bonding substrates, to the use of such composition filling depressions, cracks or holes in a substrate or between substrates to a method for bonding substrates using said composition, and to a repair method for filling depressions, cracks or holes in a substrate or between substrates using said composition.

  本发明涉及一种可固化的双组分粘合剂组合物，其第一部分包括一种或多种氰基丙烯酸酯单体、一种或多种（甲基）丙烯酸酯单体、每种化合物以及可选的控制粘度和流变性的添加剂；第二部分包括：非反应性稀释剂和过渡金属催化剂，以及可选的氰基丙烯酸酯富电子引发剂。它还涉及包含所述双组分可固化组合物的注射器或注射筒，涉及使用这种组合物粘合基材，涉及使用这种组合物填补基材或基材之间的凹陷、裂缝或孔洞，涉及使用所述组合物粘合基材的方法，以及涉及使用所述组合物填补基材或基材之间的凹陷、裂缝或孔洞的修复方法。