tris(1-(4-methoxyphenyl)ethoxy)(phenyl)silane | 1536256-33-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: tris(1-(4-methoxyphenyl)ethoxy)(phenyl)silane
• 英文别名: PhSi(OCH(Me)(p-OMeC6H4))3
• CAS: 1536256-33-3
• 化学式: C₃₃H₃₈O₆Si
• 分子量: 558.747
• InChiKey: KRWGTEGKOHYDAE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.19
• 重原子数：
  40.0
• 可旋转键数：
  13.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  55.38
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为产物：
  描述：

  苯硅烷 、 对甲氧基苯乙酮 在 [NEt₄][(cyclopentadienyl)Fe(CO)₂] 作用下， 以 neat (no solvent) 为溶剂， 反应 0.17h， 以90%的产率得到tris(1-(4-methoxyphenyl)ethoxy)(phenyl)silane
  参考文献：
  名称：

  CpFe(CO)2 阴离子催化的酮和醛的高效氢化硅烷化

  摘要：

  K[CpFe(CO) 2 ] 和 [NEt 4 ][CpFe(CO) 2 ] 使酮和醛与 PhSiH 3高效氢化硅烷化，以优异的产率合成三和双（烷氧基）硅烷，具体取决于其上的取代基羰基化合物。该催化剂代表了最有效和最实用的铁催化剂之一，用于羰基化合物的氢化硅烷化，TOF 可达 24 540 h -1。

  DOI：

  10.1039/d1dt01778k

文献信息

• A Pentacoordinate Mn(II) Precatalyst That Exhibits Notable Aldehyde and Ketone Hydrosilylation Turnover Frequencies
  作者：Chandrani Ghosh、Tufan K. Mukhopadhyay、Marco Flores、Thomas L. Groy、Ryan J. Trovitch

  DOI：10.1021/acs.inorgchem.5b01825

  日期：2015.11.2

  found to possess an intermediate-spin (S = 3/2) Mn(II) center by the Evans method and electron paramagnetic resonance spectroscopy. Furthermore, (κ5-N,N,N,N,N-PyEtPDEA)Mn was determined to be an effective precatalyst for the hydrosilylation of aldehydes and ketones, exhibiting turnover frequencies of up to 2475 min–1 when employed under solvent-free conditions. This optimization allowed for isolation

  在吡啶取代的双（亚氨基）吡啶配体PyEt PDI存在下加热（THF）2 MnCl 2，制备相应的二卤化物配合物（PyEt PDI）MnCl 2。使用过量的Na / Hg的这种前体的还原导致螯合物甲基基团的脱质子化，得到双（烯酰胺）三（吡啶） -支持的产品，（κ 5 - Ñ，Ñ，Ñ，Ñ，ñ - PyEt PDEA）的Mn 。该配合物通过单晶X射线衍射表征，发现具有中间自旋（S = 3 /2）通过Evans方法和电子顺磁共振波谱法测定Mn（II）中心。此外，（κ 5 - Ñ，Ñ，Ñ，Ñ，ñ - PyEt PDEA）Mn为确定为醛和酮的氢化硅烷化的有效预催化剂，表现出向上的周转频率2475分钟-1时溶剂下使用免费条件。这种优化可以分离出相应的醇，在两种情况下，还可以分离出部分反应的甲硅烷基醚PhSiH（OR）2 [R = Cy和CH（Me）（n Bu）]。对于（κ观察到的醛氢化硅烷化活性5 - ñ，N，N，N，N
• Hydrosilylation of Aldehydes and Ketones Catalyzed by a 2-Iminopyrrolyl Alkyl-Manganese(II) Complex
  作者：Tiago F. C. Cruz、Luís F. Veiros、Pedro T. Gomes

  DOI：10.1021/acs.inorgchem.1c03621

  日期：2022.1.17

  that of complex 2 corresponds to a monomer with a distorted tetrahedral coordination geometry. Complex 2 proved to be a very active precatalyst for the atom-economic hydrosilylation of several aldehydes and ketones under very mild conditions, with a maximum turnover frequency of 95 min–1, via a silyl-Mn(II) mechanistic route, as asserted by a combination of experimental and theoretical efforts, the respective

  提出了一种定义明确且非常活跃的单组分锰 (II) 催化剂体系，用于醛和酮的氢化硅烷化。一、5-( 2,4,6- i Pr 3 C 6 H 2 )-2-[ N -( 2,6- i Pr 2 C 6 H 3 )甲亚氨基]吡咯钾( KL )与[ MnCl 2 (Py) 2 ] 得到双核 2-亚氨基吡咯基锰 (II) 氯化吡啶络合物 [Mn 2 κ 2 N , N' -5-(2,4,6- i Pr 3 C 6 H2 )-NC 4 H 2 -2-C(H)=N(2,6- i Pr 2 C 6 H 3 )} 2 (Py) 2 (μ-Cl) 2 ] 1。随后，配合物1与 LiCH 2 SiMe 3的烷基化反应得到相应的 (三甲基甲硅烷基)甲基-Mn(II)配合物 [Mnκ 2 N , N' -5-(2,4,6- i Pr 3 C 6 ) H 2 )-NC 4 H 2 -2-C(H)=N(2,6- i Pr
• A Highly Active Manganese Precatalyst for the Hydrosilylation of Ketones and Esters
  作者：Tufan K. Mukhopadhyay、Marco Flores、Thomas L. Groy、Ryan J. Trovitch

  DOI：10.1021/ja4116346

  日期：2014.1.22

  The reduction of ((PDI)-P-Ph2PPr)MnCl2 allowed the preparation of the formally zerovalent complex, ((PDI)-P-Ph2PPr)Mn, which features a pentadentate bis(imino)pyridine chelate. This complex is a highly active precatalyst for the hydrosilylation of ketones, exhibiting TOFs of up to 76,800 h(-1) in the absence of solvent. Loadings as low as 0.01 mol % were employed, and ((PDI)-P-Ph2PPr)Mn was found to mediate the atom-efficient utilization of Si-H bonds to form quaternary silane products. ((PDI)-P-Ph2PPr)Mn was also shown to catalyze the dihydrosilylation of esters following cleavage of the substrate acyl C-O bond. Electronic structure investigation of ((PDI)-P-Ph2PPr)Mn revealed that this complex possesses an unpaired electron on the metal center, rendering it likely that catalysis takes place following electron transfer to the incoming carbonyl substituent.