syn,Z-CH3O2CC(Sn(C4H9)3)CHCHCHCH3 | 1011497-77-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: syn,Z-CH3O2CC(Sn(C4H9)3)CHCHCHCH3
• 英文别名: methyl (2Z,4Z)-2-tributylstannylhexa-2,4-dienoate
• CAS: 1011497-77-0
• 化学式: C₁₉H₃₆O₂Sn
• 分子量: 415.204
• InChiKey: RWQLMFQLMDQZPL-ZMTYPOMCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.05
• 重原子数：
  22
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (Z)-1-propenyltributyltin 、 丙炔酸甲酯 在 tris(dibenzylideneacetone)dipalladium (0) 作用下， 以 二氯甲烷 为溶剂， 生成 syn,Z-CH3O2CC(Sn(C4H9)3)CHCHCHCH3 、 syn,E-CH3O2CC(Sn(C4H9)3)CHCHCHCH3
  参考文献：
  名称：

  Alkynes as Stille Reaction Pseudohalides:  Gold- and Palladium-Cocatalyzed Synthesis of Tri- and Tetra-Substituted Olefins

  摘要：

  A Stille-type reaction that employs alkynes as pseudohalides provides access to the catalytic chemistry of palladium-carbon sigma-bonds starting from pi-systems. The synthesis of a variety of tri- and tetra-substituted olefins by addition of sp(2)- and sp-hybridized stannanes across mono- and diester alkynes was accomplished with complete regioselectivity and high stereoselectivity. The reaction is proposed to proceed via a bimetallic mechanism where the Lewis acidic Au(I) activates the alkyne toward oxidative addition across Pd(0).

  DOI：

  10.1021/ja710648b