2,3,4,6-tetra-O-benzoyl-glucopyranosyl bromide | 1174233-18-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2,3,4,6-tetra-O-benzoyl-glucopyranosyl bromide
• 英文别名: [3,4,5-Tris(benzoyloxy)-6-bromooxan-2-yl]methyl benzoate；(3,4,5-tribenzoyloxy-6-bromooxan-2-yl)methyl benzoate
• CAS: 1174233-18-1
• 化学式: C₃₄H₂₇BrO₉
• 分子量: 659.487
• InChiKey: WISFGQOOKBVKPD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  44
• 可旋转键数：
  13
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  114
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  3-butyl-N-[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]-3-phenylheptanamide 、 2,3,4,6-tetra-O-benzoyl-glucopyranosyl bromide 在 silver trifluoromethanesulfonate 作用下， 以 二氯甲烷 为溶剂， 以90%的产率得到
  参考文献：
  名称：

  Amphiphiles for protein solubilization and stabilization

  摘要：

  该发明提供了用于操纵膜蛋白的两性分子。这些两性分子可以具有碳水化合物衍生的亲水基团以及在亲水部分和/或疏水部分中的分支点。这种两性分子可用作溶解和稳定膜蛋白的洗涤剂，包括从细菌膜中获得的光合蛋白超组装体。

  公开号：

  US08263754B2

文献信息

• TIMOSAPONIN COMPOUNDS
  申请人：Che Chiming

  公开号：US20150050367A1

  公开（公告）日：2015-02-19

  Provided herein are timosaponin compounds of Formula I, II, III, I′, II′ and III′, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are uses of said timosaponin compounds for preparing medicament for the treatment of diseases associated with beta-amyloid in hosts or subjects in need thereof.

  本文提供了公式I、II、III、I'、II'和III'的timosaponin化合物、含有该化合物的制药组合物以及其制备过程。还提供了使用该timosaponin化合物制备药物用于治疗与beta-淀粉样蛋白在宿主或需要该药物的受试者相关的疾病的用途。
• [EN] PROCESS FOR THE PREPARATION OF (S,S)-SECOISOLARICIRESINOL DIGLUCOSIDE AND (R,R)-SECOISOLARICIRESINOL DIGLUCOSIDE<br/>[FR] PRÉPARATION DE (S,S)-SÉCOISOLARICIRÉSINOL DIGLUCOSIDE ET DE (R,R)-SÉCOISOLARICIRÉSINOL DIGLUCOSIDE
  申请人：LIGNAMED LLC

  公开号：WO2018231691A1

  公开（公告）日：2018-12-20

  Provided is a synthesis process for (S,S)-secoisolariciresinol diglucoside and (R,R)-secoisolariciresinol diglucoside.

  提供了一种(S,S)-丝光木素二葡萄糖苷和(R,R)-丝光木素二葡萄糖苷的合成过程。
• PROCESS FOR THE PREPARATION OF (S,S
  申请人：LignaMed, LLC

  公开号：EP3638220A1

  公开（公告）日：2020-04-22
• Anti-Adhesive Compounds to Prevent and Treat Bacterial Infections
  申请人：Berglund Jenny

  公开号：US20080171706A1

  公开（公告）日：2008-07-17

  The present invention provides compounds and compositions capable of inhibiting the attachment of Gram-negative bacteria on a host epithelium. Accordingly, said compounds and compositions can for example be used for the manufacture of a medicament to treat urinary, lung and gastrointestinal infections caused by said Gram-negative bacteria
• Solid-Phase and Solution-Phase Synthesis of Glycosylphosphatidylinositol Glycans
  申请人：Seeberger Peter H.

  公开号：US20120003260A1

  公开（公告）日：2012-01-05

  One aspect of the present invention relates to solution-phase approaches to GPI synthesis. Another aspect of the present invention relates to key building blocks, and syntheses thereof, useful for GPI assembly. Yet another aspect of the invention relates to an automated method for the synthesis of GPIs and fragments thereof.