2-Ethyl-4-acetoxy-buttersaeure | 42125-00-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Ethyl-4-acetoxy-buttersaeure
• 英文别名: 2-Ethyl-4-acetoxybutanoic acid；4-acetyloxy-2-ethylbutanoic acid
• CAS: 42125-00-8
• 化学式: C₈H₁₄O₄
• 分子量: 174.197
• InChiKey: ZLVYTUFYMZCSDA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• GABA conjugates and methods of use thereof
  申请人：Xgene Pharmaceutical Inc.

  公开号：US10478412B2

  公开（公告）日：2019-11-19

  In one aspect, the present invention provides a composition of a covalent conjugate of a GABA analog with a drug. In another aspect, the present invention provides methods for treating pain and neurological disorders using the conjugates of GABA analogs.

  一方面，本发明提供了一种 GABA 类似物与药物共价结合物的组合物。另一方面，本发明提供了使用 GABA 类似物共轭物治疗疼痛和神经系统疾病的方法。
• GABA CONJUGATES AND METHODS OF USE THEREOF
  申请人：Kyphia Pharmaceuticals, Inc.

  公开号：EP2344447A2

  公开（公告）日：2011-07-20
• ORAL WASH FOR ORAL FLUID COLLECTION AND ANALYSIS AND METHODS OF USE THEREOF
  申请人：Decimadx LLC

  公开号：EP3880312A2

  公开（公告）日：2021-09-22
• POINT-OF-CARE IMMUNOASSAY FOR QUANTITATIVE SMALL ANALYTE DETECTION
  申请人：Decimadx, LLC

  公开号：US20220276234A1

  公开（公告）日：2022-09-01

  Point-of-care assays for quantitatively measuring the amount of small analytes, such as opioids, tetrahydrocannabinol (“THC”), or hormones, in a biological sample are disclosed. The assays are capable of non-competitive detection of a small analyte using binding agents that selectively bind the analyte and capture agents that selectively bind a complex of the binding agent and analyte but do not bind either free binding agent or free analyte. The assay is capable of simultaneous diction of multiple analytes for multiplex analysis and quantitative control. Quantitative measurements are obtained by plotting results against a response surface calculated from a plurality of analyte standards and adjusted using internal controls.
• US8268887B2
  申请人：——

  公开号：US8268887B2

  公开（公告）日：2012-09-18