α-Amino-β-butyl-β-propylpropionsaeure | 103907-00-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: α-Amino-β-butyl-β-propylpropionsaeure
• 英文别名: 2-Amino-3-propyl-heptansaeure；2-Amino-3-propylheptanoic acid
• CAS: 103907-00-2
• 化学式: C₁₀H₂₁NO₂
• 分子量: 187.282
• InChiKey: ZSMLVLSRAHMTQT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  63.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• DETERMINING SMALL MOLECULE-PROTEIN AND PROTEIN-PROTEIN INTERACTIONS
  申请人：President and Fellows of Harvard College

  公开号：US20200140388A1

  公开（公告）日：2020-05-07

  Provided herein are methods, systems, kits, and compositions useful for determining small molecule-protein interactions and protein-protein interactions. The photo-click tags provided herein can be conjugated to a small molecule or amino acid analog to provide compounds that can be integrated into a protein through photo-conjugation, allowing for identification of a small molecule-protein interaction or protein-protein interaction to elucidate the small molecules mechanism of action or the protein targeted by the small molecule. In some embodiments, the photo-click tags comprise a photo-conjugation moiety and a click chemistry handle, allowing for the attachment of various functional groups (e.g., affinity tags) to the small molecule or amino acid analog.