N-phenyl-3-(1'-acetoxybutyl)-5-dibromomethylene-2(5H)pyrrolinone | 664336-48-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯啉
• 英文名称: N-phenyl-3-(1'-acetoxybutyl)-5-dibromomethylene-2(5H)pyrrolinone
• 英文别名: 1-[5-(Dibromomethylidene)-2-oxo-1-phenylpyrrol-3-yl]butyl acetate
• CAS: 664336-48-5
• 化学式: C₁₇H₁₇Br₂NO₃
• 分子量: 443.135
• InChiKey: PRVWWBHFHMGTFR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  46.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  N-phenyl-3-(1'-hydroxybutyl)-5-dibromomethylene-2(5H)pyrrolinone 在 三乙胺 、 乙酰氯 作用下， 以 二氯甲烷 为溶剂， 生成 N-phenyl-3-(1'-acetoxybutyl)-5-dibromomethylene-2(5H)pyrrolinone
  参考文献：
  名称：

  [EN] FURANONE DERIVATIVES AND METHODS OF MAKING SAME
  [FR] DERIVES DE FURANONE ET LEURS PROCEDES DE PRODUCTION

  摘要：

  本发明涉及新颖的合成方法，新方法的产物以及这些产物的用途。特别地，本发明提供了一种将呋喃酮（尤其是fimbrolides）与胺反应的方法。本发明在卤代1,5-二氢吡咯-2-酮，5-卤代亚甲基取代的1,5-二氢吡咯-2-酮（fimbrolides的内酰胺类似物），5-氨基取代呋喃酮和5-氨基亚甲基-2（5H）-呋喃酮及其合成类似物的合成中具有特定应用。本发明还涉及新化合物及其用途。

  公开号：

  WO2004016588A1

文献信息

• Hydroxamate compositions
  申请人：Covidien LP

  公开号：EP2564859A1

  公开（公告）日：2013-03-06

  The present disclosure provides compositions including a first component including at least one phospholipid possessing at least one vinyl group, a second component including a furanone possessing vinyl and/or acrylate groups, and a third component including a hydroxamate. Compositions, medical devices, and coatings including copolymers and blends of the foregoing components are also provided.

  本公开提供的组合物包括：第一组分（包括至少一种具有至少一个乙烯基的磷脂）、第二组分（包括一种具有乙烯基和/或丙烯酸酯基团的呋喃酮）和第三组分（包括一种羟肟酸酯）。此外，还提供了包括上述组分的共聚物和混合物的组合物、医疗器械和涂料。
• HYDROXAMATE COMPOSITIONS
  申请人：Stopek Joshua

  公开号：US20100093846A1

  公开（公告）日：2010-04-15

  The present disclosure provides compositions including a first component including at least one phospholipid possessing at least one vinyl group, a second component including a furanone possessing vinyl and/or acrylate groups, and a third component including a hydroxamate. Compositions, medical devices, and coatings including copolymers and blends of the foregoing components are also provided.
• ANTIMICROBIAL MATERIALS AND COATINGS
  申请人：Stopek Joshua B.

  公开号：US20100119695A1

  公开（公告）日：2010-05-13

  An antimicrobial material is provided for use in forming textiles, medical devices, packaging materials, and the like, or coatings thereon. In some embodiments, the antimicrobial material may be utilized for bulk modification of an article. The antimicrobial material includes a furanone possessing vinyl and/or acrylate functional groups, optionally in combination with another monomer possessing vinyl and/or acrylate groups.
• FURANONE COPOLYMERS
  申请人：Stopek Joshua B.

  公开号：US20100130713A1

  公开（公告）日：2010-05-27

  The present disclosure provides copolymers including a first monomer including at least one phospholipid possessing at least one vinyl group and a second monomer including a furanone possessing vinyl and/or acrylate groups. Compositions, medical devices, and coatings including such copolymers are also provided.
• Furanone Copolymers
  申请人：Stopek Joshua B.

  公开号：US20110280824A1

  公开（公告）日：2011-11-17

  The present disclosure provides copolymers including a first monomer including at least one phospholipid possessing at least one vinyl group and a second monomer including a furanone possessing vinyl and/or acrylate groups. Compositions, medical devices, and coatings including such copolymers are also provided.