7,13,21,27-tetraphenyl-29,31-bis[(N-(1-naphthalenylmethyl)aminocarbonyl)methoxy]-30,32-dihydroxy-2,4,16,18-tetrahomo-3,17-dioxacalix[4]arene | 1141747-33-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 7,13,21,27-tetraphenyl-29,31-bis[(N-(1-naphthalenylmethyl)aminocarbonyl)methoxy]-30,32-dihydroxy-2,4,16,18-tetrahomo-3,17-dioxacalix[4]arene
• 英文别名: 2-[[30,31-dihydroxy-32-[2-hydroxy-2-(naphthalen-1-ylmethylimino)ethoxy]-5,13,19,27-tetraphenyl-9,23-dioxapentacyclo[23.3.1.13,7.111,15.117,21]dotriaconta-1(29),3(32),4,6,11,13,15(31),17(30),18,20,25,27-dodecaen-29-yl]oxy]-N-(naphthalen-1-ylmethyl)ethanimidic acid
• CAS: 1141747-33-2
• 化学式: C₈₀H₆₆N₂O₈
• 分子量: 1183.41
• InChiKey: NSLPWLXHLQUACZ-UHFFFAOYSA-N

物化性质

• 熔点：
  140-141 °C
• 密度：
  1.234±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  17.1
• 重原子数：
  90
• 可旋转键数：
  14
• 环数：
  13.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  143
• 氢给体数：
  4
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  7,13,21,27-tetraphenyl-29,31-bis[(N-(1-naphthalenylmethyl)aminocarbonyl)methoxy]-30,32-dihydroxy-2,4,16,18-tetrahomo-3,17-dioxacalix[4]arene 、 N-[(chloromethyl)carbonyl]-1-pyrenemethylamine 在 potassium carbonate 、 potassium iodide 作用下， 以 乙腈 为溶剂， 反应 120.0h， 以72%的产率得到7,13,21,27-tetraphenyl-29,31-bis[(N-(1-naphthalenylmethyl)aminocarbonyl)methoxy]-30,32-bis[[N-(1-pyrenylmethyl)eminocarbonyl]-methoxy]-2,4,16,18-tetrahomo-3,17-dioxacalix[4]arene
  参考文献：
  名称：

  Metal ion induced FRET On–Off in naphthyl-pyrenyl pendent tetrahomodioxacalix[4]arene

  摘要：

  A novel tetrahomodioxacalix[4]arene (7) bearing both naphthyl- and pyrenyl-amide pendants was synthesized as FRET-based fluorometric sensor for Cu2+ ion. Intramolecular FRET from the naphthalene emission to the pyrene absorption affords Cu2+ ion selectivity over other metal ions. Upon addition of Cu2+ ion, the complex solution of 7 gave a significantly decreased pyrene acceptor emission along with an enhancement of naphthalene donor emission via FRET On-Off event. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.02.083
• 作为产物：
  描述：

  2-chloro-N-naphthalen-1-yl-methyl-acetamide 、 7,13,21,27-tetraphenyl-29,30,31,32-tetrahydroxy-2,3,16,17-tetrahomo-3,17-dioxacalix[4]arene 在 potassium carbonate 、 potassium iodide 作用下， 以 丙酮 为溶剂， 反应 80.0h， 以80%的产率得到7,13,21,27-tetraphenyl-29,31-bis[(N-(1-naphthalenylmethyl)aminocarbonyl)methoxy]-30,32-dihydroxy-2,4,16,18-tetrahomo-3,17-dioxacalix[4]arene
  参考文献：
  名称：

  Metal ion induced FRET On–Off in naphthyl-pyrenyl pendent tetrahomodioxacalix[4]arene

  摘要：

  A novel tetrahomodioxacalix[4]arene (7) bearing both naphthyl- and pyrenyl-amide pendants was synthesized as FRET-based fluorometric sensor for Cu2+ ion. Intramolecular FRET from the naphthalene emission to the pyrene absorption affords Cu2+ ion selectivity over other metal ions. Upon addition of Cu2+ ion, the complex solution of 7 gave a significantly decreased pyrene acceptor emission along with an enhancement of naphthalene donor emission via FRET On-Off event. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.02.083

文献信息

• Metal ion induced FRET On–Off in naphthyl-pyrenyl pendent tetrahomodioxacalix[4]arene
  作者：Ji Hee Jung、Min Hee Lee、Hyun Jung Kim、Hyo Sung Jung、Su Yeon Lee、Na Ri Shin、Kwanghyun No、Jong Seung Kim

  DOI：10.1016/j.tetlet.2009.02.083

  日期：2009.4

  A novel tetrahomodioxacalix[4]arene (7) bearing both naphthyl- and pyrenyl-amide pendants was synthesized as FRET-based fluorometric sensor for Cu2+ ion. Intramolecular FRET from the naphthalene emission to the pyrene absorption affords Cu2+ ion selectivity over other metal ions. Upon addition of Cu2+ ion, the complex solution of 7 gave a significantly decreased pyrene acceptor emission along with an enhancement of naphthalene donor emission via FRET On-Off event. (C) 2009 Elsevier Ltd. All rights reserved.