allyl N-[4-(4-aminophenoxy)phenyl]carbamate | 255905-11-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: allyl N-[4-(4-aminophenoxy)phenyl]carbamate
• 英文别名: prop-2-enyl N-[4-(4-aminophenoxy)phenyl]carbamate
• CAS: 255905-11-4
• 化学式: C₁₆H₁₆N₂O₃
• 分子量: 284.315
• InChiKey: QAVBJQCSQVLJDX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  73.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  nicotinoyl imidazolide 、 allyl N-[4-(4-aminophenoxy)phenyl]carbamate 以 N,N-二甲基甲酰胺 为溶剂， 反应 72.0h， 生成 prop-2-enyl N-[4-[4-(pyridine-3-carbonylamino)phenoxy]phenyl]carbamate
  参考文献：
  名称：

  Synthesis of Phenoxyphenyl Pyridine and Pyrazine Carboxamides. Activity against Cydia pomonella (L.) Eggs

  摘要：

  Several N-(4-phenoxyphenyl)pyridinecarboxamides and N-(4-phenoxyphenyl)pyrazinecarboxamides were synthesized from commercially available material, and their ovicidal activities against Cydia pomonella (L.) were tested. Some of the tested products showed a moderate activity when <24-h-old eggs were sprayed using a Potter tower. A significant increase in the length of the development also observed in many cases. A clear correlation between both effects was period of the eggs was noticed: the products that produced higher mortality also produced higher increase of the length of the development. These results seem to confirm our hypothesis that these compounds could be defined as a juvenile hormone analogues.

  DOI：

  10.1021/jf990404e
• 作为产物：
  描述：

  4,4'-二氨基二苯醚 、 氯甲酸烯丙酯 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 1.0h， 以27%的产率得到allyl N-[4-(4-aminophenoxy)phenyl]carbamate
  参考文献：
  名称：

  Synthesis of Phenoxyphenyl Pyridine and Pyrazine Carboxamides. Activity against Cydia pomonella (L.) Eggs

  摘要：

  Several N-(4-phenoxyphenyl)pyridinecarboxamides and N-(4-phenoxyphenyl)pyrazinecarboxamides were synthesized from commercially available material, and their ovicidal activities against Cydia pomonella (L.) were tested. Some of the tested products showed a moderate activity when <24-h-old eggs were sprayed using a Potter tower. A significant increase in the length of the development also observed in many cases. A clear correlation between both effects was period of the eggs was noticed: the products that produced higher mortality also produced higher increase of the length of the development. These results seem to confirm our hypothesis that these compounds could be defined as a juvenile hormone analogues.

  DOI：

  10.1021/jf990404e

文献信息

• Synthesis of Phenoxyphenyl Pyridine and Pyrazine Carboxamides. Activity against <i>Cydia pomonella</i> (L.) Eggs
  作者：Mercè Balcells、Jesús Avilla、Jaume Profitos、Ramon Canela

  DOI：10.1021/jf990404e

  日期：2000.1.1

  Several N-(4-phenoxyphenyl)pyridinecarboxamides and N-(4-phenoxyphenyl)pyrazinecarboxamides were synthesized from commercially available material, and their ovicidal activities against Cydia pomonella (L.) were tested. Some of the tested products showed a moderate activity when <24-h-old eggs were sprayed using a Potter tower. A significant increase in the length of the development also observed in many cases. A clear correlation between both effects was period of the eggs was noticed: the products that produced higher mortality also produced higher increase of the length of the development. These results seem to confirm our hypothesis that these compounds could be defined as a juvenile hormone analogues.