N-ethylidene-p-toluidine | 74753-03-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-ethylidene-p-toluidine
• 英文别名: Acetaldehyd-p-tolylimid；N-Aethyliden-p-toluidin
• CAS: 74753-03-0
• 化学式: C₉H₁₁N
• 分子量: 133.193
• InChiKey: XORXGKZDROIMHY-XCVCLJGOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.72
• 重原子数：
  10.0
• 可旋转键数：
  1.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  12.36
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  乙烷,三氯氟- 、 乙醛 生成 N-ethylidene-p-toluidine
  参考文献：
  名称：

  Schiff, Justus Liebigs Annalen der Chemie, 1866, vol. 140, p. 96

  摘要：

  DOI：

文献信息

• METHOD FOR PRODUCING AROMATIC COMPOUND
  申请人：Sumitomo Chemical Company, Limited

  公开号：US20150322101A1

  公开（公告）日：2015-11-12

  A method is provided for producing an aromatic compound, including a step of mixing a compound represented by formula (A) and a compound represented by formula (B): in the presence of at least one phosphine compound selected from the group consisting of a phosphine represented by formula (C) and a phosphonium salt represented by formula (F): a base, a palladium compound, and an aprotic organic solvent.

  提供一种生产芳香化合物的方法，包括以下步骤：在至少一种磷化物化合物的存在下，将由化学式(A)表示的化合物与由化学式(B)表示的化合物混合；所述磷化物化合物选择自由化学式(C)表示的磷化物和由化学式(F)表示的磷酸盐；还包括碱、钯化合物和无水有机溶剂。
• [EN] PHENYLACETAMIDES AS INHIBITORS OF ROCK<br/>[FR] PHÉNYLACÉTAMIDES UTILISÉS EN TANT QU'INHIBITEURS DE ROCK
  申请人：BRISTOL MYERS SQUIBB CO

  公开号：WO2019014300A1

  公开（公告）日：2019-01-17

  The present invention provides compounds of Formula (I): Formula (I) or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.

  本发明提供了以下式（I）的化合物：式（I）或其立体异构体、互变异构体或其药用可接受的盐，其中所有变量如本文所定义。这些化合物是选择性ROCK抑制剂。本发明还涉及包含这些化合物的药物组合物以及使用这些药物组合物治疗心血管、平滑肌、肿瘤学、神经病理学、自身免疫、纤维化和/或炎症性疾病的方法。
• Polymer compound and polymer light emitting device
  申请人：Yamamoto Takakazu

  公开号：US20120200808A1

  公开（公告）日：2012-08-09

  To provide a polymer compound which is useful as a light emitting material or charge transport material having a boron atom. A polymer compound comprising a structure represented by a formula (1) as described below: wherein R 1 , R 2 , and R 3 each independently represents a hydrogen atom or a substituent.

  提供一种聚合物化合物，可用作具有硼原子的发光材料或电荷传输材料。包括以下公式（1）所表示的结构的聚合物化合物：其中R1、R2和R3分别独立表示氢原子或取代基。
• Organic electroluminescence device
  申请人：Uetani Yasunori

  公开号：US20090015139A1

  公开（公告）日：2009-01-15

  An organic electroluminescence device wherein a light emitting layer exists between electrodes composed of an anode and a cathode, a layer (L) containing a polymer compound exists between the light emitting layer and the anode and the polymer compound contains a repeating unit of the following formula (1): (wherein, Ar 1 , Ar 2 , Ar 3 and Ar 4 represent each independently an arylene group or divalent heterocyclic group. E 1 , E 2 and E 3 represent each independently the following aryl group (A) or heterocyclic group (B). a and b represent each independently 0 or 1, and 0≦a+b≦1. Aryl group (A): aryl group having three or more substituents selected from alkyl groups, alkoxy groups and the like, Heterocyclic group (B): monovalent heterocyclic group having one or more substituents selected from alkyl groups, alkoxy groups and the like and in which the sum of the number of the substituents and the number of hetero atoms of the heterocycle is 3 or more.).

  一种有机电致发光器件，其包含一个发光层，该发光层位于由阳极和阴极组成的电极之间。在发光层和阳极之间存在一个含有聚合物化合物的层（L），该聚合物化合物包含以下式（1）的重复单元：（其中，Ar1，Ar2，Ar3和Ar4分别独立地表示芳基基团或二价杂环基团。E1，E2和E3分别独立地表示以下芳基基团（A）或杂环基团（B）。a和b分别独立地表示0或1，且0≦a+b≦1。芳基基团（A）：具有三个或更多取代基（例如烷基、烷氧基等）的芳基基团，杂环基团（B）：具有一个或多个取代基（例如烷基、烷氧基等）的一价杂环基团，且杂环的取代基数和杂原子数之和为3或更多）。
• LIGHT EMITTING POLYMER COMPOSITION AND POLYMER LIGHT EMITTING DEVICE
  申请人：Uetani Yasunori

  公开号：US20090039765A1

  公开（公告）日：2009-02-12

  A light emitting polymer composition comprising a light emitting polymer and a compound selected from the following formulae (1a) to (1d): (wherein, X represents an atom or atomic group forming a 5-membered or 6-membered ring together with four carbon atoms on two benzene rings in the formula, Q and T represent each independently a hydrogen atom, halogen atom, alkyl group, alkyloxy group, alkylthio group, aryl group, aryloxy group, arylthio group, arylalkyl group, arylalkyloxy group, arylalkylthio group, alkenyl group, alkynyl group, arylalkenyl group, arylalkynyl group, substituted silyloxy group, substituted silylthio group, substituted silylamino group, substituted amino group, amide group, acid imide group, acyloxy group, mono-valent heterocyclic group, heteroaryloxy group, heteroarylthio group, cyano group or nitro group).

  一种发光聚合物组合物，包括一种发光聚合物和从以下公式（1a）至（1d）中选择的化合物：（其中，X代表与公式中两个苯环上的四个碳原子一起形成5元环或6元环的原子或原子团，Q和T分别独立地代表氢原子、卤素原子、烷基、烷氧基、烷硫基、芳基、芳氧基、芳硫基、芳基烷基、芳基烷氧基、芳基烷硫基、烯基、炔基、芳基烯基、芳基炔基、取代硅氧基、取代硅硫基、取代硅氨基、取代氨基、酰胺基、酸亚胺基、酰氧基、单价杂环基、杂芳氧基、杂芳硫基、氰基或硝基）。