diethyl ethylmalonate sodium salt | 18995-13-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: diethyl ethylmalonate sodium salt
• CAS: 18995-13-6
• 化学式: C₉H₁₅NaO₄
• 分子量: 210.205
• InChiKey: DLGOEOXZGDTGBF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.26
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  36.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  diethyl ethylmalonate sodium salt 、 2-溴溴苄 以 乙醇 为溶剂， 生成 Diethyl 2-(2-bromobenzyl)-2-ethylmalonate
  参考文献：
  名称：

  DE2733868

  摘要：

  公开号：

文献信息

• Radical–nucleophilic substitution (S_RN1) reactions: preparation and reactions of α-nitrosuiphides
  作者：W. Russell Bowman、Geoffrey D. Richardson

  DOI：10.1039/p19800001407

  日期：——

  α-Nitrosulphides were prepared by SRN1 reaction of 2-bromo-2-nitropropane with thiolate anions, and by SN2 attack of sodium 2-nitropropan-2-ide on symmetrical disulphides. The α-nitrosulphides undergo radicalnucleophilic substitution (SRN1) by nitronate, sulphinate, and malonate anions, but not by thiolate anions.

  α-亚硝基硫化物是通过2-溴-2-硝基丙烷与硫醇根阴离子的S RN 1反应，以及2-硝基丙烷-2-化钠对对称二硫化物的S N 2攻击而制备的。α-亚硝基硫化物通过亚硝酸根，亚磺酸根和丙二酸根阴离子进行自由基亲核取代（S RN 1），但不被硫醇根阴离子取代。
• Remarkable Ligand Effects in Regioselective Palladium-Catalysed Allylic Substitution Reactions
  作者：Lara Acemoglu、Jonathan M. J. Williams

  DOI：10.1002/1615-4169(20010129)343:1<75::aid-adsc75>3.0.co;2-w

  日期：2001.1.29

  The use of tricyclohexylphosphine (and related phosphines) in palladium-catalysed allylic substitution reactions enables the selective conversion of branched allylic acetates into the branched substitution products (up to 120:1 regioselectivity). Linear allylic acetates do not show the same selectivity for the branched substitution products, thereby demonstrating a memory effect.

  在钯催化的烯丙基取代反应中使用三环己基膦（及相关的膦）可以将支链烯丙基乙酸酯选择性转化为支链取代产物（区域选择性高达120：1）。线性烯丙基乙酸酯对支链取代产物没有显示出相同的选择性，从而表现出记忆效应。
• Novel radical chain substitution reaction involving single electron transfer SET processes
  作者：Rui Tamura、Kunihiko Yamawaki、Nagao Azuma

  DOI：10.1021/jo00020a004

  日期：1991.9

  Beta-Substituted alpha[(phenylsulfonyl)methyl]- and alpha-z[(phenylthio)methyl]cyclohexenones 1-4 underwent regioselective replacement of the sulfonyl and sulfenyl groups by stabilized carbanions such as LiCMe2NO2 mainly by a radical chain mechanism, which was confirmed by investigating the effects of photoirradiation, radical scavengers, and reaction solvents and by the ESR and spectroscopic studies.