2,2'-methylenebis[6-(2H-benzotriazole-2-yl)-4-(3-hydroxypropyl)phenol] | 196516-63-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2'-methylenebis[6-(2H-benzotriazole-2-yl)-4-(3-hydroxypropyl)phenol]
• 英文别名: 2-(benzotriazol-2-yl)-6-[[3-(benzotriazol-2-yl)-2-hydroxy-5-(3-hydroxypropyl)phenyl]methyl]-4-(3-hydroxypropyl)phenol
• CAS: 196516-63-9
• 化学式: C₃₁H₃₀N₆O₄
• 分子量: 550.617
• InChiKey: QJBFVUOARWYJJC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  41
• 可旋转键数：
  10
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  142
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  2-(2H-benzotriazole-2-yl)-4-(3-hydroxypropyl)-6-(N,N-diethylaminomethyl)phenol 、 、 2-(2H-benzotriazole-2-yl)-4-(3-hydroxypropyl)phenol 、 甲醇 、 sodium methylate 在 氮 作用下， 以 邻二甲苯 为溶剂， 反应 10.0h， 以giving 33.0 g of 2,2'-methylenebis[6-(2H-benzotriazole-2-yl)-4-(3-hydroxypropyl)phenol] as white crystals (yield 61.2%, purity 99.0%)的产率得到2,2'-methylenebis[6-(2H-benzotriazole-2-yl)-4-(3-hydroxypropyl)phenol]
  参考文献：
  名称：

  Bisbenzotriazolylphenol compound

  摘要：

  本发明的目的是提供一种具有紫外线吸收效果的新型双苯并三氮唑基酚类化合物。该发明的双苯并三氮唑基酚类化合物由下式表示：##STR1##其中，A是直接键或表示C.sub.1-6烷基、--C(CH.sub.3).sub.2--基团、--C(C.sub.2H.sub.5)(CH.sub.3)--基团、--O--基团或--NH--基团；R.sup.1和R.sup.3相同或不同，且分别表示氢原子、C.sub.1-4烷基、芳基、C.sub.1-4烷氧基或卤素原子；R.sup.2和R.sup.4相同或不同，且分别表示羟基或C.sub.1-12直链或支链羟基烷基。

  公开号：

  US05922882A1

文献信息

• Alkyl amino acid derivatives useful as pharmaceutical agents
  申请人：WARNER-LAMBERT COMPANY

  公开号：EP1178034A1

  公开（公告）日：2002-02-06

  GABA-related pro-drugs of the formula (III) are provided that when administered to humans or other mammals provide an increased duration of active compound in the plasma compared to compounds of corresponding structure in which labile groups are not present. The compounds are of the formula (III) In the above formula: P represents hydrogen or methyl; Q represents a labile amine- or amide-forming organic group that becomes removed in the human or animal body; R1 represents straight or branched C2 - C6 alkyl, C3 - C6 cycloalkyl or phenyl; R2 represents hydrogen or methyl; and R3 represents hydrogen, methyl or carboxyl; and R4 represents hydrogen or a labile ester-forming group selected from substituted and unsubstituted C1 - C6 alkyl, benzyl and phenyl groups that become removed in the human or animal body. In the above formula when R1 is phenyl, R2, R3 and R4 are not simultaneously hydrogen. Pharmaceutically acceptable salts of any salt-forming compound within the above class are also included. The compounds may be used to treat a range of neurological conditions, e.g. epilepsy and pain.

  提供了公式（III）的GABA相关的前药，当给人类或其他哺乳动物使用时，与相应结构中不存在不稳定基团的化合物相比，在血浆中提供了较长的活性化合物持续时间。该化合物的公式为（III）： 在上述公式中： P代表氢或甲基； Q代表不稳定胺或酰胺形成的有机基团，在人体或动物体内被去除； R1代表直链或支链C2-C6烷基，C3-C6环烷基或苯基； R2代表氢或甲基； R3代表氢，甲基或羧基； R4代表氢或不稳定酯形成基团，选择自取代和未取代的C1-C6烷基，苄基和苯基，在人体或动物体内被去除。 在上述公式中，当R1为苯基时，R2、R3和R4不同时为氢。还包括上述类别中任何盐形成化合物的药学上可接受的盐。这些化合物可用于治疗一系列神经系统疾病，例如癫痫和疼痛。
• BISBENZOTRIAZOLYLPHENOLS
  申请人：OTSUKA KAGAKU KABUSHIKI KAISHA

  公开号：EP0855393A1

  公开（公告）日：1998-07-29

  An object of the present invention is to provide a novel bisbenzotriazolylphenol compound having a UV absorving effect. The bisbenzotriazolylphenol compound of the invention is represented by the formula wherein A is a direct bond or represents a C1-6 alkylene group, a -C(CH3)2- group, a -C(C2H5)(CH3)- group, a -O- group or a -NH- group, R1 and R3 are the same or different and each represent a hydrogen atom, a C1-4 alkyl group, an aryl group, a C1-4 alkoxy group or a halogen atom, and R2 and R4 are the same or different and each represent a hydroxyl group or a C1-12 straight- or branched-chain hydroxyalkyl group.

  本发明的目的是提供一种具有紫外线吸收效果的新型双苯并三唑基苯酚化合物。本发明的双苯并三唑基苯酚化合物由式表示 其中 A 是直接键或代表 C1-6 亚烷基、-C(CH3)2- 基团、-C(C2H5)( )- 基团、-O- 基团或-NH- 基团，R1 和 R3 相同或不同，各自代表氢原子、C1-4 烷基、芳基、C1-4 烷氧基或卤原子，R2 和 R4 相同或不同，各自代表羟基或 C1-12 直链或支链羟烷基。
• WEATHER-RESISTANT COMPOSITION, COATING MATERIALS AND MOLDED ARTICLES
  申请人：OTSUKA CHEMICAL COMPANY, LIMITED

  公开号：EP1104790A1

  公开（公告）日：2001-06-06

  The present invention relates to a weather-resistant composition comprising a bisbenzotriazolylphenol compound represented by the general formula (1): [wherein A represents an alkylene group, and R1 and R2 represent a group (B): (in which R3 and R4 represent an alkyl group)], a (meth)acrylate compound, and a curing agent; a coating material containing the weather-resistant composition as a main component; and a molded article. The composition can form a coating film which is not impaired in mechanical strength, exhibits excellent weather resistance, metal ion resistance and transparency for a prolonged period, and is less likely to cause surface cracks.

  本发明涉及一种耐候性组合物，该组合物包含通式（1）所代表的双苯并三唑酚化合物： [其中 A 代表亚烷基，R1 和 R2 代表基团 (B)： (其中 R3 和 R4 代表烷基）]、(甲基)丙烯酸酯化合物和固化剂；含有该耐候性组合物作为主要成分的涂层材料；以及成型制品。该组合物可形成一层涂膜，该涂膜的机械强度不受损害，具有出色的耐候性、耐金属离子性和长时间的透明度，并且不易产生表面裂纹。
• SEALING FILM FOR SOLAR CELL AND SOLAR CELL USING THE SAME
  申请人：Bridgestone Corporation

  公开号：EP2216828A1

  公开（公告）日：2010-08-11

  A sealing film for a solar cell is provided, which has excellent ultraviolet resistance. The sealing film for a solar cell according to the present invention includes ethylene-vinyl acetate copolymer; an organic peroxide; a benzotriazole-based ultraviolet absorber; and a hindered amine-based light stabilizer. The content of the benzotriazole-based ultraviolet stabilizer is in the range of 0.01 to 0.3 parts by weight, based on 100 parts by weight of ethylene-vinyl acetate copolymer. Further, the content of the hindered amine-based light stabilizer is in the range of 0.01 to 2 parts by weight, based on 100 parts by weight of ethylene-vinyl acetate copolymer.

  本发明提供了一种太阳能电池密封膜，它具有优异的抗紫外线性能。根据本发明，太阳能电池密封膜包括乙烯-醋酸乙烯共聚物、有机过氧化物、苯并三唑类紫外线吸收剂和受阻胺类光稳定剂。苯并三唑类紫外线稳定剂的含量范围为 0.01 至 0.3 重量份（以 100 重量份乙烯-醋酸乙烯共聚物为基准）。此外，以 100 份乙烯-醋酸乙烯共聚物的重量为基准，受阻胺类光稳定剂的含量在 0.01 至 2 份的重量范围内。
• SEALING FILM FOR SOLAR CELL
  申请人：Adeka Corporation

  公开号：EP2511958A1

  公开（公告）日：2012-10-17

  Provided is a sealing film for a solar battery which has excellent light resistance and heat resistance by preventing yellowing due to the influence of light or heat. The sealing film for a solar battery, in which 0.05-10 parts by weight of a hindered amine compound having a substructure represented by the following general formula (I): (wherein R1, R2, R3, and R4 each independently represent C1-C4 lower alkyl; and R represents hydrogen, C1-C18 straight- or branched-chain alkyl which may be substituted by hydroxy, or C5-C8 cycloalkyl) based on 100 parts by weight of an ethylene-vinyl acetate copolymer is blended.

  本发明提供了一种太阳能电池密封膜，它具有优异的耐光性和耐热性，可防止因光或热的影响而变黄。 该太阳能电池密封膜中含有 0.05-10 重量份的受阻胺化合物，其子结构由以下通式（I）表示： (其中 R1、R2、R3 和 R4 各自独立地代表 C1-C4 低级烷基；R 代表氢、C1-C18 直链或支链烷基（可被羟基取代）或 C5-C8 环烷基），以 100 份（重量）乙烯-醋酸乙烯共聚物为基准。