R-α-cyano-3-phenoxybenzyl R-α-isopropylphenylacetate | 73436-48-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: R-α-cyano-3-phenoxybenzyl R-α-isopropylphenylacetate
• 英文别名: [Cyano-(3-phenoxyphenyl)methyl] 3-methyl-2-phenyl-butanoate；[cyano-(3-phenoxyphenyl)methyl] 3-methyl-2-phenylbutanoate
• CAS: 73436-48-3
• 化学式: C₂₅H₂₃NO₃
• 分子量: 385.463
• InChiKey: PMLDHOYHYKUBCZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  29
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  59.3
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Process for the preparation of alpha-cyanobenzyl esters
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0003242A1

  公开（公告）日：1979-08-08

  A process for the preparation of alpha-cyanobenzyl esters of general formula (I): characterized in that a carboxylic acid halide of general formula (II): is reacted with an alpha-cyanobenzyi alcohol of general formula (III): in the presence of a Lewis acid catalyst, wherein in the general formulae A is an optionally-substituted aralkyl, alkyl or cycloalkyl group containing up to 24 carbon atoms; X is an alkyl, alkenyl, aralkyl or aryloxy group containing up to 10 carbon atoms; n is an integer of 1 to 3; and halide is bromine or chlorine.

  一种通式(I)的α-氰基苄酯的制备方法： 其特征在于，通式（II）的羧酸卤化物 与通式（III）的α-氰基苯甲醇反应： 在路易斯酸催化剂存在下，其中通式中的 A 是含有最多 24 个碳原子的任选取代的芳基、烷基或环烷基；X 是含有最多 10 个碳原子的烷基、烯基、芳基或芳氧基；n 是 1 至 3 的整数；卤化物是溴或氯。
• Aqueous formulations of parasiticides for skin applications
  申请人：——

  公开号：US20030162773A1

  公开（公告）日：2003-08-28

  The present invention relates to water-containing formulations for the dermal control of parasitic insects on animals, having the following composition a) agonists or antagonists of the nicotinic acetylcholine receptors of insects in a concentration of from 1 to 20% by weight based on the overall weight of the formulation; b) water in a concentration of from 2.5 to 15% by weight; c) solvents from the group alcohols such as benzyl alcohol, tetrahydrofuryl alcohol or optionally substituted pyrrolidones in a concentration of at least 20% by weight based on the overall weight of the formulation; d) solvents from the group of the cyclic carbonates or lactones in a concentration of from 5 to up to 50% by weight based on the overall weight of the formulation; e) if desired, further auxiliaries from the group thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, adhesives, emulsifiers, in a concentration of from 0.025 up to 10% by weight based on the overall weight of the formulation.

  本发明涉及用于皮肤防治动物身上寄生昆虫的含水制剂，其成分如下 a) 昆虫烟碱乙酰胆碱受体的激动剂或拮抗剂，浓度为制剂总重量的 1%至 20%（按重量计）； b) 水，浓度为 2.5%至 15%（按重量计）； c) 醇类溶剂，如苯甲醇、四氢糠醇或任选取代的吡咯烷酮，浓度至少为制剂总重量的 20%（以重量百分比计）； d) 环碳酸酯类或内酯类溶剂，浓度为 5%至 50%（以制剂总重量为基准）； e) 如果需要，还可以添加增稠剂、铺展剂、着色剂、抗氧化剂、推进剂、防腐剂、 粘合剂、乳化剂等助剂，其浓度为 0.025 至 10%（按配方总重量计算）。
• US4153626A
  申请人：——

  公开号：US4153626A

  公开（公告）日：1979-05-08
• US4350642A
  申请人：——

  公开号：US4350642A

  公开（公告）日：1982-09-21
• US4526727A
  申请人：——

  公开号：US4526727A

  公开（公告）日：1985-07-02