1-[(1R,2R,3S,4S,5S,6S)-2,3,4-Tris-benzyloxy-5,6-bis-(4-methoxy-benzyloxy)-cyclohexyl]-prop-2-en-1-ol | 220206-44-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-[(1R,2R,3S,4S,5S,6S)-2,3,4-Tris-benzyloxy-5,6-bis-(4-methoxy-benzyloxy)-cyclohexyl]-prop-2-en-1-ol
• CAS: 220206-44-0
• 化学式: C₄₆H₅₀O₈
• 分子量: 730.898
• InChiKey: AASPXEPGQLMQJC-FWGWHYAVSA-N

反应信息

• 作为反应物：
  描述：

  1-[(1R,2R,3S,4S,5S,6S)-2,3,4-Tris-benzyloxy-5,6-bis-(4-methoxy-benzyloxy)-cyclohexyl]-prop-2-en-1-ol 生成 Toluene-4-sulfonic acid 3-methoxymethoxy-3-[(1R,2R,3S,4S,5S,6S)-2,3,4-tris-benzyloxy-5,6-bis-(4-methoxy-benzyloxy)-cyclohexyl]-propyl ester
  参考文献：
  名称：

  Synthesis of Bicyclic Derivatives of 5a-Carba-sugars: 6-Hydroxyl Group Conformationally Restricted 5a-Carba-D-mannopyranose Derivatives

  摘要：

  Some bicyclic derivatives of 5a-carba-alpha- and beta-D-mannopyranoses, whose 6-hydroxyl groups are conformationally restricted, have been synthesized in order to provide key components of the trisaccharide mimics designed as inhibitors or substrate analogues useful for elucidation of mechanism and action of GlcNAcT-V.

  DOI：

  10.3987/com-98-s(h)42
• 作为产物：
  描述：

  (1R,2R,3S,4S,5S,6S)-2,3,4-Tris-benzyloxy-5,6-bis-(4-methoxy-benzyloxy)-cyclohexanecarbaldehyde 、 [(1R,2R,3S,4S,5S,6S)-2,3,4-Tris-benzyloxy-5,6-bis-(4-methoxy-benzyloxy)-cyclohexyl]-methanol 、 乙炔基溴化镁 在 草酰氯 、 二甲基亚砜 作用下， 以 二氯甲烷 、 四氢呋喃 为溶剂， 以80%的产率得到1-[(1R,2R,3S,4S,5S,6S)-2,3,4-Tris-benzyloxy-5,6-bis-(4-methoxy-benzyloxy)-cyclohexyl]-prop-2-en-1-ol
  参考文献：
  名称：

  Synthesis of Bicyclic Derivatives of 5a-Carba-sugars: 6-Hydroxyl Group Conformationally Restricted 5a-Carba-D-mannopyranose Derivatives

  摘要：

  Some bicyclic derivatives of 5a-carba-alpha- and beta-D-mannopyranoses, whose 6-hydroxyl groups are conformationally restricted, have been synthesized in order to provide key components of the trisaccharide mimics designed as inhibitors or substrate analogues useful for elucidation of mechanism and action of GlcNAcT-V.

  DOI：

  10.3987/com-98-s(h)42