5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)furan-3-carboxylic acid | 1211569-94-6

分子结构分类

有机化合物 - 苯类化合物 - 苯和取代衍生物

中文名称

——

中文别名

——

英文名称

5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)furan-3-carboxylic acid

英文别名

5-[[(4-methoxy-2,6-dimethylphenyl)sulfonyl-methylamino]methyl]furan-3-carboxylic acid

CAS

1211569-94-6

化学式

C₁₆H₁₉NO₆S

mdl

——

分子量

353.396

InChiKey

NDZXRYNYFCOZGS-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

1.9
重原子数：

24
可旋转键数：

6
环数：

2.0
sp3杂化的碳原子比例：

0.31
拓扑面积：

105
氢给体数：

1
氢受体数：

7

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	ethyl 5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)furan-3-carboxylate	1211569-93-5	C₁₈H₂₃NO₆S	381.45

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-[2-(4-{[(2-methylpropyl)amino]methyl}phenyl)ethyl]furan-3-carboxamide	1211570-66-9	C₂₉H₃₉N₃O₅S	541.712
——	5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-[3-(pyrrolidin-1-ylmethyl)benzyl]furan-3-carboxamide	1211570-16-9	C₂₈H₃₅N₃O₅S	525.669
——	5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-[4-(pyrrolidin-1-ylmethyl)benzyl]furan-3-carboxamide	1211570-60-3	C₂₈H₃₅N₃O₅S	525.669
——	5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-{2-[4-(pyrrolidin-1-ylmethyl)phenyl]ethyl}furan-3-carboxamide	1211570-71-6	C₂₉H₃₇N₃O₅S	539.696
——	5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-methyl-N-[3-(pyrrolidin-1-ylmethyl)benzyl]furan-3-carboxamide	1211570-13-6	C₂₉H₃₇N₃O₅S	539.696
——	5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-methyl-N-[4-(pyrrolidin-1-ylmethyl)benzyl]furan-3-carboxamide	1211570-14-7	C₂₉H₃₇N₃O₅S	539.696
——	4-methoxy-N,2,6-trimethyl-N-[(4-{[4-(2-pyrrolidin-1-ylethyl)piperazin-1-yl]carbonyl}furan-2-yl)methyl]benzenesulfonamide	1211570-62-5	C₂₆H₃₈N₄O₅S	518.678
——	4-methoxy-N,2,6-trimethyl-N-[(4-{[4-(pyridin-4-ylmethyl)piperazin-1-yl]carbonyl}furan-2-yl)methyl]benzenesulfonamide	1211570-56-7	C₂₆H₃₂N₄O₅S	512.63
——	N-{4-[(3-hydroxyazetidin-1-yl)methyl]benzyl}-5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-methylfuran-3-carboxamide	1211573-28-2	C₂₈H₃₅N₃O₆S	541.668
——	4-methoxy-N,2,6-trimethyl-N-[(4-{[4-(2-morpholin-4-ylethyl)piperazin-1-yl]carbonyl}furan-2-yl)methyl]benzenesulfonamide	1211570-57-8	C₂₆H₃₈N₄O₆S	534.677
——	N-[4-(4,5-dihydro-1H-imidazol-2-yl)benzyl]-5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)furan-3-carboxamide	1211570-07-8	C₂₆H₃₀N₄O₅S	510.614
——	4-methoxy-N,2,6-trimethyl-N-[(4-{[4-(pyrrolidin-1-ylmethyl)piperidin-1-yl]carbonyl}furan-2-yl)methyl]benzenesulfonamide	1211570-65-8	C₂₆H₃₇N₃O₅S	503.663
——	N-{4-[(3-methoxyazetidin-1-yl)methyl]benzyl}-5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-methylfuran-3-carboxamide	1211573-34-0	C₂₉H₃₇N₃O₆S	555.695
——	N-{4-[(4-hydroxypiperidin-1-yl)methyl]benzyl}-5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-methylfuran-3-carboxamide	1211573-25-9	C₃₀H₃₉N₃O₆S	569.722
——	4-methoxy-N,2,6-trimethyl-N-{[4-({4-[(1-methylpiperidin-4-yl)methyl]piperazin-1-yl}carbonyl)furan-2-yl]methyl}benzenesulfonamide	1211570-54-5	C₂₇H₄₀N₄O₅S	532.704
——	N-{4-[(3-hydroxypyrrolidin-1-yl)methyl]benzyl}-5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-methylfuran-3-carboxamide	1211573-37-3	C₂₉H₃₇N₃O₆S	555.695
——	4-methoxy-N,2,6-trimethyl-N-[(4-{[4-(1-methylpiperidin-4-yl)piperazin-1-yl]carbonyl}furan-2-yl)methyl]benzenesulfonamide	1211569-95-7	C₂₆H₃₈N₄O₅S	518.678
——	5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-methyl-N-(4-pyrimidin-5-ylbenzyl)furan-3-carboxamide	1211570-61-4	C₂₈H₃₀N₄O₅S	534.636
——	4-methoxy-N,2,6-trimethyl-N-[(4-{[4-(2-pyridin-4-ylethyl)piperazin-1-yl]carbonyl}furan-2-yl)methyl]benzenesulfonamide	1211570-55-6	C₂₇H₃₄N₄O₅S	526.657
——	5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-{4-[(4-methoxypiperidin-1-yl)methyl]benzyl}-N-methylfuran-3-carboxamide	1211573-26-0	C₃₁H₄₁N₃O₆S	583.749
——	4-methoxy-N,2,6-trimethyl-N-{[4-({4-[(1-methylpiperidin-3-yl)methyl]piperazin-1-yl}carbonyl)furan-2-yl]methyl}benzenesulfonamide	1211570-53-4	C₂₇H₄₀N₄O₅S	532.704
——	N-{2-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]ethyl}-5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)furan-3-carboxamide	1211570-02-3	C₂₇H₃₂N₄O₅S	524.641
——	N-{4-[(4-aminopyrimidin-2-yl)amino]benzyl}-5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)furan-3-carboxamide	1211570-21-6	C₂₇H₃₀N₆O₅S	550.638
——	N-[4-(4,5-dihydro-1H-imidazol-2-yl)benzyl]-5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-methylfuran-3-carboxamide	1211570-51-2	C₂₇H₃₂N₄O₅S	524.641
——	N-[4-(1H-imidazol-1-yl)benzyl]-5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-methylfuran-3-carboxamide	1211569-97-9	C₂₇H₃₀N₄O₅S	522.625
——	5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-{4-[(3-methoxypyrrolidin-1-yl)methyl]benzyl}-N-methylfuran-3-carboxamide	1211573-30-6	C₃₀H₃₉N₃O₆S	569.722
——	N-(4-{[3-(dimethylamino)pyrrolidin-1-yl]methyl}benzyl)-5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-methylfuran-3-carboxamide	1211573-39-5	C₃₁H₄₂N₄O₅S	582.764
——	5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-(1,2,2,6,6-pentamethylpiperidin-4-yl)furan-3-carboxamide	1211570-00-1	C₂₆H₃₉N₃O₅S	505.679
——	5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-methyl-N-[4-(1,4,5,6-tetrahydropyrimidin-2-yl)benzyl]furan-3-carboxamide	1211570-15-8	C₂₈H₃₄N₄O₅S	538.668
——	N-(2-{4-[(4-aminopyrimidin-2-yl)amino]phenyl}ethyl)-5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)furan-3-carboxamide	1211570-69-2	C₂₈H₃₂N₆O₅S	564.665
——	5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-{2-[4-(4-methyl-4,5-dihydro-1H-imidazol-2-yl)phenyl]ethyl}furan-3-carboxamide	1211570-10-3	C₂₈H₃₄N₄O₅S	538.668
——	N-{2-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]ethyl}-5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-methylfuran-3-carboxamide	1211570-04-5	C₂₈H₃₄N₄O₅S	538.668
——	5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-{4-[(3-methoxypiperidin-1-yl)methyl]benzyl}-N-methylfuran-3-carboxamide	1211573-31-7	C₃₁H₄₁N₃O₆S	583.749
——	5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-methyl-N-[4-(1-methyl-1H-imidazol-2-yl)benzyl]furan-3-carboxamide	1211570-67-0	C₂₈H₃₂N₄O₅S	536.652
——	N-(2-{4-[(2-aminopyrimidin-4-yl)amino]phenyl}ethyl)-5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)furan-3-carboxamide	1211570-70-5	C₂₈H₃₂N₆O₅S	564.665
——	N-(4-{[3-(acetylamino)pyrrolidin-1-yl]methyl}benzyl)-5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-N-methylfuran-3-carboxamide	1211573-33-9	C₃₁H₄₀N₄O₆S	596.748
——	1-(4-{[{[5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)furan-3-yl]carbonyl}(methyl)amino]methyl}benzyl)-N,N-dimethylpyrrolidine-3-carboxamide	1211573-32-8	C₃₂H₄₂N