| 1192425-01-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• CAS: 1192425-01-6
• 化学式: C₂₁H₃₀FN₃O₃S
• 分子量: 423.552
• InChiKey: ZCWTVXHWRMQANH-WKILWMFISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  29.0
• 可旋转键数：
  5.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  74.43
• 氢给体数：
  2.0
• 氢受体数：
  4.0

文献信息

• COMPOUNDS HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY
  申请人：SAKAGAMI Masahiro

  公开号：US20120130070A1

  公开（公告）日：2012-05-24

  This invention provides a compound of the formula (I): a pharmaceutically acceptable salt or solvate thereof, wherein R 1 is substituted or unsubstituted alkyl or the like, R 2 is hydrogen or substituted or unsubstituted alkyl, Ring A is monocyclic or bicyclic aromatic heterocycle, R 3 is substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl or substituted or unsubstituted heterocycle, R 4 is halogen, cyano, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl or the like, m is an integer between 0 and 2, n is an integer between 0 and 5, R is halogen, oxo, cyano, nitro, substituted or unsubstituted alkyl or the like, and p is an integer between 0 and 2 as novel compounds having NPY Y5 antagonistic activity.
• US8299066B2
  申请人：——

  公开号：US8299066B2

  公开（公告）日：2012-10-30