L-Glutamic acid, N-[carboxy(2-nitrophenyl)methyl]- | 158078-66-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: L-Glutamic acid, N-[carboxy(2-nitrophenyl)methyl]-
• 英文别名: (2S)-2-[[carboxy-(2-nitrophenyl)methyl]amino]pentanedioic acid
• CAS: 158078-66-1
• 化学式: C13H14N2O8
• 分子量: 326.26
• InChiKey: QOZVGBSQVLPBRK-YMNIQAILSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.9
• 重原子数：
  23
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  170
• 氢给体数：
  4
• 氢受体数：
  9

文献信息

• [EN] METHODS FOR MODULATING NEURAL ACTIVITY IN THE RETINA<br/>[FR] MODULATION DE L'ACTIVITE NEURONALE DANS LA RETINE
  申请人：UNIV WASHINGTON

  公开号：WO2002074176A1

  公开（公告）日：2002-09-26

  In one aspect, the present invention provides methods for modulating neural activity in the retina of a mammalian eye, wherein the methods each comprise the step of irradiating the retina of a mammalian eye with light energy (14,16,18,22,26), wherein: (a) the retina comprises a photoactivatable precursor molecule comprising a neuroactive molecule linked to a photoabsorbent molecule; and (b) the light energy releases the neuroactive molecule from the photoabsorbent molecule, the released neuroactive molecule interacting with one or more retinal neurons thereby modulating neural activity in the retina.