4-Hydroxy-2-methylpyrrolidine-2-carboxylic acid hydrochloride | 1955493-30-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 4-Hydroxy-2-methylpyrrolidine-2-carboxylic acid hydrochloride
• 英文别名: 4-hydroxy-2-methylpyrrolidine-2-carboxylic acid;hydrochloride
• CAS: 1955493-30-7
• 化学式: C6H12ClNO3
• 分子量: 181.62
• InChiKey: RZGXNFGNTRVIGN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.39
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  69.6
• 氢给体数：
  4
• 氢受体数：
  4

文献信息

• AMIDE DERIVATIVES FOR GPR119 AGONIST
  申请人：CHONG KUN DANG PHARMACEUTICAL CORP.

  公开号：US20170129875A1

  公开（公告）日：2017-05-11

  The present invention relates to novel amide derivatives, stereoisomers thereof or pharmaceutically acceptable salts thereof; methods for preparing the compound; and pharmaceutical compositions comprising the compound. The novel amide derivatives, according to the present invention, having an effect as GPR119 agonist can be used for treatment of metabolic disorders, including diabetes mellitus (especially type II) and related disorders.
• US9776987B2
  申请人：——

  公开号：US9776987B2

  公开（公告）日：2017-10-03