bis(p-methoxyphenyl) phosphonate | 15516-40-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: bis(p-methoxyphenyl) phosphonate
• CAS: 15516-40-2
• 化学式: C₁₄H₁₅O₅P
• 分子量: 294.244
• InChiKey: GNZJOZHFFGNPND-UHFFFAOYSA-N

物化性质

• 沸点：
  430.0±30.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.55
• 重原子数：
  20.0
• 可旋转键数：
  6.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  53.99
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  bis(p-methoxyphenyl) phosphonate 在 cesium fluoride 作用下， 生成 bis(4-methoxyphenyl) α-methoxybenzylphosphonate
  参考文献：
  名称：

  Photolysis of Diary Triphenylmethylphosphonates

  摘要：

  摘要。在甲醇中紫外线照射下，二芳基三苯甲基磷酸酯经历了三种类型的消除反应，去除两个芳基，形成了双芳烃：第一种是从三苯甲基基团中α,α-消除两苯基，导致相应的卡宾中间体的形成；第二种是从二芳基酯基团中消除两个芳基，以生成双芳烃；第三种是从两个部分消除苯基和芳基，生成芳基苯。

  DOI：

  10.1246/bcsj.63.1269

文献信息

• Catalytic Enantioselective Protonation of α-Oxygenated Ester Enolates Prepared through Phospha-Brook Rearrangement
  作者：Masashi Hayashi、Shuichi Nakamura

  DOI：10.1002/anie.201007568

  日期：2011.3.1

  chiral: The organocatalytic enantioselective reaction of α‐ketoesters with phosphites using cinchona alkaloids and Na2CO3 has afforded α‐phosphonyloxy esters with high enantioselectivities (see scheme). This process allows the formation of both enantiomers of the product. A catalyst loading of as low as 2 mol % does not result in a significant decrease of the enantioselectivity.

  膦酸酯变为手性：使用金鸡纳生物碱和Na 2 CO 3，α-酮酸酯与亚磷酸酯的有机催化对映选择性反应提供了高对映选择性的α-膦酰氧基酯（参见方案）。该过程允许形成产物的两种对映异构体。低至2mol％的催化剂负载量不会导致对映选择性的显着降低。
• METHOD FOR MANUFACTURING TRICYCLODECANE MONO-METHANOL MONOCARBOXYLIC ACID DERIVATIVE
  申请人：Kawakami Hiroyuki

  公开号：US20120203026A1

  公开（公告）日：2012-08-09

  Provided is a method for manufacturing a tricyclodecane mono-methanol monocarboxylic acid derivative that can be used as a raw material for high heat-resistant alicyclic polyesters and the like. The provided method for manufacturing a tricyclodecane mono-methanol monocarboxylic acid derivative is characterized in that a tricyclodecane mono-methanol monocarboxylic acid derivative represented by the following formula (III) is obtained by reacting the dicyclopentadiene represented by the following formula (I) with a formic acid compound in the presence of a catalytic system containing a ruthenium compound, a cobalt compound, and a halide salt, to give a tricyclodecene monocarboxylic acid derivative represented by the formula (II), and then hydroformylating the tricyclodecene monocarboxylic acid derivative. (in the formulae (II) and (III), R represents a hydrogen, an alkyl group having 1 to 5 carbon atoms, a vinyl group, or a benzyl group.)

  提供了一种制造三环十二烷基单甲醇单羧酸衍生物的方法，可用作高耐热脂环聚酯等的原材料。所提供的制造三环十二烷基单甲醇单羧酸衍生物的方法的特点在于，通过在含有钌化合物、钴化合物和卤化盐的催化体系存在下，将以下式（I）所代表的二环戊二烯与甲酸化合物反应，得到以下式（II）所代表的三环十二烯单羧酸衍生物，然后对三环十二烯单羧酸衍生物进行氢甲酰化反应，得到以下式（III）所代表的三环十二烷基单甲醇单羧酸衍生物。（在式（II）和（III）中，R代表氢、含有1至5个碳原子的烷基、乙烯基或苄基。）
• Preparation of <i>Z</i>-α,β-Unsaturated Diazoketones from Aldehydes. Application in the Construction of Substituted Dihydropyridin-3-ones
  作者：Isac G. Rosset、Antonio C. B. Burtoloso

  DOI：10.1021/jo401191s

  日期：2013.9.20

  The stereoselective preparation of α,β-unsaturated diazoketones with Z geometry is described from aldehydes and a new olefination reagent. When prepared from amino aldehydes, these diazoketones could be converted to substituted dihydropyridin-3-ones in just one step, after an intramolecular N–H insertion reaction. The straightforward synthesis of a natural trihydroxylated piperidine demonstrates the

  从醛和一种新的烯烃化试剂描述了具有Z几何形状的α，β-不饱和重氮酮的立体选择性制备。当由氨基醛制备时，在分子内NH插入反应后，仅一步即可将这些重氮酮转化为取代的二氢吡啶-3-酮。天然三羟基化哌啶的直接合成证明了这些不饱和重氮酮对哌啶的快速构建的实用性。
• Direct Enantioselective Three-Component Kabachnik-Fields Reaction Catalyzed by Chiral Bis(imidazoline)-Zinc(II) Catalysts
  作者：Mutsuyo Ohara、Shuichi Nakamura、Norio Shibata

  DOI：10.1002/adsc.201100482

  日期：2011.12

  A direct three-component reaction of aldehydes, amines and diaryl phosphites was catalyzed by a zinc(II) complex of 1,3-bis(imidazolin-2-ly)pyridine (pybim) giving the corresponding α-aminophosphonates in good yield with good enantioselectivity. The reaction was applied to a wide variety of aromatic aldehydes to give products with excellent yields (up to 99%) and enantiomeric excesses (up to 93% ee)

  1,3-双（咪唑啉-2-ly）吡啶（pybim）的锌（II）络合物催化醛，胺和亚磷酸二芳酯的直接三组分反应，从而以高收率和良好收率得到相应的α-氨基膦酸酯对映选择性。反应可用于多种芳族醛，可制得具有极佳收率（最高达99％）和对映体过量（最高达ee 93％）的产物。
• RESIN AND ARTICLE MOLDED THEREFROM
  申请人：TORAY INDUSTRIES, INC.

  公开号：EP1640405A1

  公开（公告）日：2006-03-29

  The resin of the invention comprises both a phosphorus-containing residue having a bicycloalkyl structure and a specific divalent phenol residue. The invention provides a resin having excellent optical properties, which is colorless and transparent, has a high refractive index and is optically low dispersive, as well as its molded product.

  本发明的树脂由具有双环烷基结构的含磷残基和特定的二价酚残基组成。本发明提供了一种具有优异光学性能的树脂及其模塑产品，该树脂无色透明，折射率高，光学色散性低。