4-(羧基甲基)-[1,1-联苯]-4-羧酸 | 868394-59-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-(羧基甲基)-[1,1-联苯]-4-羧酸
• 英文名称: 4'-(Carboxymethyl)-[1,1'-biphenyl]-4-carboxylic acid
• 英文别名: 4-[4-(carboxymethyl)phenyl]benzoic acid
• CAS: 868394-59-6
• 化学式: C₁₅H₁₂O₄
• 分子量: 256.258
• InChiKey: OKPOZLAJLVCWLC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2916399090

反应信息

• 作为产物：
  描述：

  4-羧基苯硼酸 、 对溴苯乙酸 在 silica-Si-(CH₂)3NH(CH₂)2NH₂-PdCl₂ sodium carbonate 作用下， 以 N,N-二甲基乙酰胺 、 水 为溶剂， 反应 2.0h， 生成 4-(羧基甲基)-[1,1-联苯]-4-羧酸
  参考文献：
  名称：

  Catalytic properties of several supported Pd(II) complexes for Suzuki coupling reactions

  摘要：

  Pd(II) complexes with N-ligands were synthesized and tested for Suzuki coupling reaction. These complexes were also heterogenized on silica. The resulting site-isolated catalysts showed a high catalytic activity. The most stable complex was supported N-(propyl)ethylenediamine, which did not display any notable leaching. The effects of reaction conditions and the nature of the boronic acid derivative on the conversion of the starting compounds were studied. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.08.029

文献信息

• Catalytic properties of several supported Pd(II) complexes for Suzuki coupling reactions
  作者：Oleksiy Vassylyev、Jengshiou Chen、Anthony P. Panarello、Johannes G. Khinast

  DOI：10.1016/j.tetlet.2005.08.029

  日期：2005.10

  Pd(II) complexes with N-ligands were synthesized and tested for Suzuki coupling reaction. These complexes were also heterogenized on silica. The resulting site-isolated catalysts showed a high catalytic activity. The most stable complex was supported N-(propyl)ethylenediamine, which did not display any notable leaching. The effects of reaction conditions and the nature of the boronic acid derivative on the conversion of the starting compounds were studied. (c) 2005 Elsevier Ltd. All rights reserved.