4-[5-(3,5-dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-2-methyl-N-((R)-2-benzyl-3-oxo-isoxazolidin-4-yl)-benzamide | 1309957-74-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 4-[5-(3,5-dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-2-methyl-N-((R)-2-benzyl-3-oxo-isoxazolidin-4-yl)-benzamide
• 英文别名: N-[(4R)-2-benzyl-3-oxo-1,2-oxazolidin-4-yl]-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-2-methylbenzamide
• CAS: 1309957-74-1
• 化学式: C₂₈H₂₂Cl₂F₃N₃O₄
• 分子量: 592.402
• InChiKey: GTZFZRWWSNQWCT-DXDQHDRFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  40
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  80.2
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• INSECTICIDAL COMPOUNDS BASED ON ISOAZOLINE DERIVATIVES
  申请人：Cassayre Jerome Yves

  公开号：US20120238517A1

  公开（公告）日：2012-09-20

  The present invention relates to compounds of formula (I): Wherein A 1 , A 2 , A 3 , A 4 , G 1 , L, Y 1 , Y 2 , Y 3 , Y 4 , R 1 , R 2 , R 3 and R 4 are as defined in claim 1 ; or a salt or N-oxide thereof. Furthermore, the present invention relates to intermediates for preparing compounds of formula (I), to compositions comprising them and to methods of using them to combat and control insect, acarine, nematode and mollusc pests.

  本发明涉及式(I)的化合物：其中A1、A2、A3、A4、G1、L、Y1、Y2、Y3、Y4、R1、R2、R3和R4如权利要求1所定义；或其盐或N-氧化物。此外，本发明涉及制备式(I)化合物的中间体，包含它们的组合物以及使用它们来对抗和控制昆虫、螨虫、线虫和软体动物害虫的方法。
• Insecticidal compounds based on isoxazoline derivatives
  申请人：Syngenta Crop Protection LLC

  公开号：US10206400B2

  公开（公告）日：2019-02-19

  The present invention relates to compounds of formula (I): wherein A1, A2, A3, A4, G1, L, Y1, Y2, Y3, Y4, R1, R2, R3 and R4 are as defined in claim 1; or a salt or N-oxide thereof. Furthermore, the present invention relates to intermediates for preparing compounds of formula (I), to compositions comprising them and to methods of using them to combat and control insect, acarine, nematode and mollusc pests.

  本发明涉及式（I）化合物： 其中 A1、A2、A3、A4、G1、L、Y1、Y2、Y3、Y4、R1、R2、R3 和 R4 如权利要求 1 所定义；或其盐或 N-氧化物。 此外，本发明还涉及制备式(I)化合物的中间体、包含它们的组合物以及使用它们防治昆虫、刺吸虫、线虫和软体动物害虫的方法。
• METHODS FOR CONTROLLING WIREWORMS
  申请人：Syngenta Participations AG

  公开号：EP2887808B1

  公开（公告）日：2019-04-24
• METHODS OF CONTROLLING INSECTS
  申请人：Syngenta Participations AG

  公开号：US20150216169A1

  公开（公告）日：2015-08-06

  The present invention relates to methods, preferably for controlling and/or preventing infestation of boll weevil in cotton, comprising applying to a crop of cotton plants, the locus thereof, or propagation material thereof, a compound of formula (I), wherein —B 1 —B 2 —B 3 — is —C═N—O—, —C═N—CH 2 —, —C═CH—O— or —N—CH 2 —CH 2 —; L is a direct bond or methylene; A 1 and A 2 are C—H, or one of A 1 and A 2 is C—H and the other is N; X 1 is group X R 1 is C 1 -C 4 alkyl, C 1 C 4 aloalkyl or C 3 -C 6 cycloalkyl; R 2 is chlorodifluoromethyl or trifluoromethyl; each R 3 is independently bromo, chloro, fluoro or trifluoromethyl; R 4 is hydrogen, halogen, methyl, halomethyl or cyano; R 5 is hydrogen; or R 4 and R 5 together form a bridging 1,3-butadiene group; p is 2 or 3.
• METHODS OF SOIL PEST CONTROL
  申请人：Syngenta Participations AG

  公开号：US20150208655A1

  公开（公告）日：2015-07-30

  The present invention relates to methods of controlling and/or preventing soil-dwelling pests in useful plants comprising applying to the locus of the useful plant or treating plant propagation material thereof with a compound of formula (I) wherein —B 1 —B 2 —B 3 — is —C═N—O—, —C═N—CH 2 —, —C═CH 2 —O— or —N—CH 2 —CH 2 —; L is a direct bond or methylene; A 1 and A 2 are C—H, or one of A 1 and A 2 is C—H and the other is N; X 1 is group X, formula (X) R 1 is C 1 -C 4 alkyl, C 1 -C 4 aloalkyl or C 3 -C 6 cycloalkyl; R 2 is chlorodifluoromethyl or trifluoromethyl; each R 3 is independently bromo, chloro, fluoro or trifluoromethyl; R 4 is hydrogen, halogen, methyl, halomethyl or cyano; R 5 is hydrogen; or R 4 and R 5 together form a bridging 1,3-butadiene group; p is 2 or 3. Preferably the soil-dwelling pest is selected from corn rootworm, wireworms, grubs, in particular white grubs (e.g. Phyllophaga sp., Diloboderus sp., Popillia japonica ), termites (in particular for sugar cane), subterraneous stinkbugs (e.g. Scaptocoris sp.), cutworms (e.g. agrotis sp.), millipedes (e.g. Julus sp.) and broca gigante (e.g. Telchin licus ).