ethyl 3-(((trimethylsilyl)oxy)imino)butanoate | 1290071-56-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: ethyl 3-(((trimethylsilyl)oxy)imino)butanoate
• CAS: 1290071-56-5
• 化学式: C₉H₁₉NO₃Si
• 分子量: 217.34
• InChiKey: XQNAQJREKJVINJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.17
• 重原子数：
  14.0
• 可旋转键数：
  5.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  47.89
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  trimethylsilyl N-trimethylsilyl-N-(trimethylsiloxy)carbamate 、 乙酰乙酸乙酯 在 三氟乙酸 作用下， 反应 4.0h， 以78%的产率得到ethyl 3-(((trimethylsilyl)oxy)imino)butanoate
  参考文献：
  名称：

  Alkyloximes and Imines via Silyl Carbamates

  摘要：

  [image omitted] The reactions between different N,O-bis-trimethylsilyl-carbamates and oxo compounds were studied. The N,O-bis-trimethylsilyl-N-methoxy-carbamate converts ketones to the corresponding O-methyl oximes. The product is usually a mixture of syn and anti isomers. If the carbonyl compound bears a hydroxyl group, the oxime formation and the O-silylation take place simultaneously. In the case of -haloketones, the undesired substitution of halogen was not observed. The reactions between N,O-bis-trimethylsilyl-N-methyl-carbamate and oxo compounds resulted in the corresponding imines, although the yield are moderate in some cases. Analoguos reaction of ferrocenylated oxo derivatives gave similar results.

  DOI：

  10.1080/00397911003707121