4-Acetamidobut-2-ynoic acid | 1935469-19-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-Acetamidobut-2-ynoic acid
• CAS: 1935469-19-4
• 化学式: C₆H₇NO₃
• 分子量: 141.12
• InChiKey: HTQCEXSKHYEJKU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• BEZIMIDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS
  申请人：Merck Patent GmbH

  公开号：EP3672952A1

  公开（公告）日：2020-07-01
• BENZIMIDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS
  申请人：Merck Patent GmbH

  公开号：EP3672952B1

  公开（公告）日：2022-12-14
• [EN] COMPOUNDS WHICH SELECTIVELY MODULATE THE CB2 RECEPTOR<br/>[FR] COMPOSÉS À MODULATION SÉLECTIVE DU RÉCEPTEUR CB2
  申请人：BOEHRINGER INGELHEIM INT

  公开号：WO2011037795A1

  公开（公告）日：2011-03-31

  Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.
• [EN] BEZIMIDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS<br/>[FR] DÉRIVÉS DE BENZIMIDAZOLE UTILISÉS EN TANT QU'ANTAGONISTES DU RÉCEPTEUR DE L'ADÉNOSINE
  申请人：MERCK PATENT GMBH

  公开号：WO2019038215A1

  公开（公告）日：2019-02-28

  The invention relates to benzimidazole derivatives of the general formula (I), and the use of the compounds of the present invention for the treatment and/or prevention of hyperproliferative or infectious diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.