2-Bromo-1,3-dimethyl-5-(trifluoromethoxy)benzene | 1798817-02-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-Bromo-1,3-dimethyl-5-(trifluoromethoxy)benzene
• CAS: 1798817-02-3
• 化学式: C₉H₈BrF₃O
• 分子量: 269.06
• InChiKey: JUTLTPAGIWZFJD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• NOVEL PHENOXUACETIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND USES OF DERIVATIVE AS DRUG
  申请人：CHINA PHARMACEUTICAL UNIVERSITY

  公开号：US20210122704A1

  公开（公告）日：2021-04-29

  The present invention relates to a novel phenoxyacetic acid derivative represented by the general formula (I), preparation method thereof and use of a pharmaceutical composition containing the derivative in preparing a medicament for treating diabetes and metabolic syndrome. The phenoxyacetic acid derivatives have excellent in vivo hypoglycemic activity, which can be used for preventing or treating diabetes.