N,N'-Dimethylazelaamid | 10044-02-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N,N'-Dimethylazelaamid
• 英文别名: N,N'-dimethyl azelaamide；N,N'-dimethylnonanediamide
• CAS: 10044-02-7
• 化学式: C₁₁H₂₂N₂O₂
• mdl: MFCD24392983
• 分子量: 214.308
• InChiKey: STVUVQYWTXFZFA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  15
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.818
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• GUANYLHYDRAZONE COMPOUNDS, COMPOSITIONS, METHODS OF MAKING AND USING
  申请人：SIELECKI-DZURDZ Thais

  公开号：US20110144189A1

  公开（公告）日：2011-06-16

  The present invention relates to compounds having the formula: salts thereof; compositions comprising one or more of the compounds and/or salts thereof; methods of using; and methods of making.
• HMGB1 EXPRESSION AND PROTECTIVE ROLE OF SEMAPIMOD IN NEC
  申请人：ZAMORA Ruben

  公开号：US20110224301A1

  公开（公告）日：2011-09-15

  Methods are described, which include the administration of semapimod or guanylhydrazone containing compounds, salt thereof, or a combination of the compound and a salt thereof for the inhibition, treatment, and/or prevention of any of NEC, a condition associated with the release of HMGB1, a condition associated with the release of iNOS protein, a condition associated with the release of Bax protein, a condition associated with the release of Bad protein, a condition associated with the release of COX-2 protein, or a condition associated with the release of RAGE, or a combination thereof to a subject in need thereof.
• US8314149B2
  申请人：——

  公开号：US8314149B2

  公开（公告）日：2012-11-20