2,2-dibutyl-N,N'-bis(2-(2-pyridyl)ethyl)malonamide | 131356-16-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2,2-dibutyl-N,N'-bis(2-(2-pyridyl)ethyl)malonamide
• 英文别名: 2,2-dibutyl-N,N'-di(2-pyridyl-2-ethyl)malonamide；2,2-dibutyl-N,N'-bis(2-pyridin-2-ylethyl)propanediamide
• CAS: 131356-16-6
• 化学式: C₂₅H₃₆N₄O₂
• 分子量: 424.586
• InChiKey: TZZSWHJYCURHQQ-UHFFFAOYSA-N

物化性质

• 沸点：
  666.7±55.0 °C(Predicted)
• 密度：
  1.072±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  31
• 可旋转键数：
  14
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  84
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  二丁基丙二酸 在 氯化亚砜 、 三乙胺 作用下， 以 苯 为溶剂， 反应 5.0h， 生成 2,2-dibutyl-N,N'-bis(2-(2-pyridyl)ethyl)malonamide
  参考文献：
  名称：

  N-(8-quinolyl)-N'-(2-pyridylmethyl)malonamide derivatives as a novel copper(II) carrier with high efficiency and selectivity for proton-driven uphill transport through liquid membranes

  摘要：

  Several N,N'-disubstituted malonamide derivatives have been designed as a carrier for ion transport. Their ability to transport transition-metal ions through liquid membranes has been investigated. It has been found that N-(8-quinolyl)-N'-(2-pyridylmethyl)malonamide derivatives can transport Cu(II) with high efficiency and selectivity against its concentration gradient from nearly a neutral aqueous phase (pH 6.2) to an acidic aqueous phase through a chloroform liquid membrane.

  DOI：

  10.1021/jo00052a019

文献信息

• A Novel Cu(II) Carrier with High Efficiency and Selectivity for Proton-driven Uphill Transport through Liquid Membranes
  作者：Kazuhisa Hiratani、Takuji Hirose、Kyoko Fujiwara、Kiyoshi Saito

  DOI：10.1246/cl.1990.1921

  日期：1990.10

  N-(8-Quinolyl)-N′-(2-pyridylmethyl)malonamide derivative, which has been synthesized as carrier for transition metal ions, can transport Cu(II) with high selectivity against its concentration gradi...

  N-(8-Quinolyl)-N'-(2-pyridylmethyl)丙二酰胺衍生物作为过渡金属离子的载体合成，可以相对于其浓度梯度高选择性地传输Cu(II)...